Results 71 to 80 of about 740,964 (300)

SARS-CoV-2 Cross-reactive T cells.

, 2021
(A) CD154 upregulation assay of potential cross-reactive epitopes. Top panel: DR0101 SARS- CoV-2 S961-980, middle panel: DR1501 SARS-CoV-2 S1001-1020, and bottom panel: DP0401 SARS-CoV-2 S809-828. SARS-CoV-2 peptide-specific cell lines were generated and
Uma Malhotra (847242), Alexandra M. Johansson (11441927), Maxwell P. Krist (11886473), Yeseul G. Kim (11886467), David M. Koelle (8138436), Rebecca Gomez (11886470), William W. Kwok (7380419), Anna Wald (172640)   +7 more
core   +1 more source

T Cell responses to whole SARS Coronavirus in humans [PDF]

, 2008
Effective vaccines should confer long-term protection against future outbreaks of severe acute respiratory syndrome (SARS) caused by a novel zoonotic coronavirus (SARS-CoV) with unknown animal reservoirs.
Douek, Daniel C., McMichael, A., Temperton, Nigel J., Lin, C.L., Tran, Bac-Hai, Brenchley, JM, Screaton, Gavin R., Yan, Huiping, Yan, H., Tran, BH, Douek, DC, Ma, Shiwu, Temperton, N., Li, Chris Ka-fai, Wu, H., Wu, Hao, Hou, Jin-lin, Yan, H, Xu, XN, Ma, S., Tran, H., Screaton, GR, Mongkolsapaya, J., Mongkolsapaya, Juthathip, McMichael, Andrew J., Ma, S, Tang, X., Weiss, R., Xu, X., Hou, JL, Wang, L., Li, C., Tang, X, Zhang, Mingxia, Weiss, RA, Wang, L, Lin, Chen-lung Steve, Weiss, Robin A., Screaton, G., Mcmichael, AJ, Lin, CL, Hou, J., Wu, H, Mcmichael, Andrew, Xu, Xiao-Ning, Brenchley, J., Brenchley, Jason M., Mongkolsapaya, J, Wang, Lili, Douek, D., Tang, Xiaoping, Li, CK, Zhang, M, Temperton, NJ, Zhang, M.   +54 more
core   +1 more source

SARS-CoV-2 Uzbekistan MetaData

, 2022
Tracking temporal and spatial genomic changes and evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Uzbekistan.
Alisher Abdullaev (12124800)
core   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Therapeutic antibodies under development for SARS‐CoV‐2

View, 2022
The world is experiencing one of the most difficult moments in history with COVID‐19, which has rapidly developed into a worldwide pandemic with a significant health and economic burden.
Zetong Ma, MengMei Zhu, Shuyi Zhang, Kewen Qian, Chuqi Wang, Wenyan Fu, Changhai Lei, Shi Hu   +7 more
doaj   +1 more source

Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 positivity.

, 2022
Prevalences of SARS-CoV-2 RNA and anti-SARS-CoV-2 positivity.
Woottichai Khamduang (147028), Porntip Phoseng (12035143), Gonzague Jourdain (96227), Siriluk Takalay (12035134), Khajornsak Tragoolpua (88183), Sakorn Pornprasert (12035152), Nantawan Wangsaeng (12035146), Paporn Mongkolwat (12035140), Wanlee Kongnim (12035137), Sayamon Hongjaisee (8357454), Nicole Ngo-Giang-Huong (147034), Bordin Butr-Indr (12035149)   +11 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Guillain‐Barré syndrome after SARS‐CoV‐2 infection

Journal of General and Family Medicine, 2022
We herein report a case of Guillain‐Barré syndrome (GBS) after SARS‐CoV‐2 infection. The patient was a close contact with a SARS‐CoV‐2 patient. Initially, she did not have any symptoms and quarantined at a hotel.
Mikiya Kajita, Masamichi Sato, Yutaka Iizuka, Yamato Mashimo, Natsumi Furuta, Satoru Kakizaki   +5 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source