Results 161 to 170 of about 1,638,503 (361)

Implementing BMP‐7 Chemically Modified RNA for Bone Regeneration with 3D Printable Hyaluronic Acid‐Collagen Granular Gels

open access: yesAdvanced Healthcare Materials, EarlyView.
This study developed 3D‐printable THA‐Col microgels for delivering BMP‐7 cmRNA. The key result is that hMSCs transfected on the biomaterials showed BMP‐7 secretion levels comparable to pre‐transfected hMSCs, therefore introducing a cmRNA‐activated matrix to promote bone healing.
Daphne van der Heide   +7 more
wiley   +1 more source

Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor

open access: yesNature, 2020
J. Lan   +10 more
semanticscholar   +1 more source

PCM-SAR: Physics-Driven Contrastive Mutual Learning for SAR Classification [PDF]

open access: yesarXiv
Existing SAR image classification methods based on Contrastive Learning often rely on sample generation strategies designed for optical images, failing to capture the distinct semantic and physical characteristics of SAR data. To address this, we propose Physics-Driven Contrastive Mutual Learning for SAR Classification (PCM-SAR), which incorporates ...
arxiv  

Nanomaterial‐Enhanced Biosensing: Mechanisms and Emerging Applications

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanomaterial integration transforms biosensor capabilities through enhanced signal transduction, sensitivity, and selectivity. This review analyzes how nanoscale materials—from nanoparticles to nanosheets—leverage unique physicochemical properties to revolutionize electrochemical, optical, and electrical biosensing.
Younghak Cho   +3 more
wiley   +1 more source

Options for combination therapy of influenza and ARVI with combined drugs

open access: yesМедицинский совет, 2015
According to the World Health Organization (WHO), 3 to 5 million cases of influenza are registered every year worldwide, of which 250--500 thousand are fatal.
T. V. Sologub   +2 more
doaj   +1 more source

RBC Membrane‐Camouflaged Nanosystem‐Mediated Synergistic Drug Combination for Enhanced Anti‐Tumor Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
An RBC membrane camouflaged, cell‐penetrating peptides R8‐based drug delivery system is constructed to achieve a synergistic combination of natural compounds triptolide (TP) and celastrol (Cel), inducing tumor cell apoptosis, reducing tumor metastasis invasion and triggering autophagy disorder in breast cancer and liver cancer.
Qian Cheng   +6 more
wiley   +1 more source

Recommendations for coronavirus infection in rheumatic diseases treated with biologic therapy. [PDF]

open access: yes, 2020
The Coronavirus-associated disease, that was first identified in 2019 in China (CoViD-19), is a pandemic caused by a bat-derived beta-coronavirus, named SARS-CoV2.
Ansari, Aftab A   +6 more
core  

Direct Surface Modification of the Epidermis Using Mussel‐Inspired Polydopamine with Multiple Anti‐Biofouling Functions

open access: yesAdvanced Healthcare Materials, EarlyView.
Surface modification using mussel‐derived polydopamine (PDA) is a versatile and robust biocompatible strategy that enables direct application to various epidermal surfaces, regardless of their morphological complexity or surface characteristics. The PDA‐coated epidermis exhibits multiple anti‐biofouling functionalities, including antibacterial and anti‐
Su Eon Lee   +14 more
wiley   +1 more source

Rational Design of Unsaturated, Thioether Ionizable Lipids for Enhanced In Vivo mRNA Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Lipid nanoparticles (LNPs) have rapidly become the delivery system of choice for RNA therapeutics. Here, a rational design approach is taken to improve the effectiveness of LNPs based on an ionizable thioether lipid library. The incorporation of unsaturated tails and bulkier, hydrophobic head groups significantly enhances their functionality and ...
Eleni Samaridou   +4 more
wiley   +1 more source

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