Targeting a key enzyme in SARS-CoV-2 Scientists across the world are working to understand severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19). Zhang et al.
Linlin Zhang+8 more
semanticscholar +1 more source
An Sveir Model for Assessing Potential Impact of an Imperfect Anti-SARS Vaccine [PDF]
The control of severe acute respiratory syndrome (SARS), a fatal contagious viral disease that spread to over 32 countries in 2003, was based on quarantine of latently infected individuals and isolation of individuals with clinical symptoms of SARS ...
Gumel, Abba B.+2 more
core +2 more sources
Trans-splicing of mRNAs links gene transcription to translational control regulated by mTOR
Background In phylogenetically diverse organisms, the 5′ ends of a subset of mRNAs are trans-spliced with a spliced leader (SL) RNA. The functions of SL trans-splicing, however, remain largely enigmatic.
Gemma B. Danks+6 more
doaj +1 more source
Neuronal gene expression in two generations of the marine parasitic worm, Cryptocotyle lingua
Trematodes, or flukes, undergo intricate anatomical and behavioral transformations during their life cycle, yet the functional changes in their nervous system remain poorly understood.
Oleg Tolstenkov+2 more
doaj +1 more source
Single-centre experience of emergency hernia surgery during COVID-19 pandemic: a comparative study of the operative activity and outcomes before and after the outbreak [PDF]
Aim The outbreak of COVID-19 pandemic in January 2020 affected largely the elective operating for non-urgent surgical pathologies, such as hernias, due to periodical cancellations of the operating lists on a worldwide scale. To the best of our knowledge,
Adnan Malik+3 more
doaj +1 more source
A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology
The ongoing pandemic spread of a new human coronavirus, SARS-CoV-2, which is associated with severe pneumonia/disease (COVID-19), has resulted in the generation of tens of thousands of virus genome sequences.
A. Rambaut+7 more
semanticscholar +1 more source
Comparative Evolution of Animal and Human Coronaviruses, their Varieties and Virulence [PDF]
Coronaviruses are a group of enveloped viruses with single-stranded and RNA genomes that cause a wide-ranging spectrum of animal and human diseases.
Shabnam Rustamani
doaj +1 more source
Evidence for Gastrointestinal Infection of SARS-CoV-2
The new coronavirus (SARS-CoV-2) outbreak originating from Wuhan, China, poses a threat to global health. While it's evident that the virus invades respiratory tract and transmits from human to human through airway, other viral tropisms and transmission ...
Fei Xiao+5 more
semanticscholar +1 more source
Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet+10 more
core +1 more source
Evolution of CDK1 Paralog Specializations in a Lineage With Fast Developing Planktonic Embryos
The active site of the essential CDK1 kinase is generated by core structural elements, among which the PSTAIRE motif in the critical αC-helix, is universally conserved in the single CDK1 ortholog of all metazoans.
Xiaofei Ma+5 more
doaj +1 more source