Results 41 to 50 of about 1,671,123 (378)

Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay. [PDF]

open access: yes, 2011
Severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged as the causal agent of an endemic atypical pneumonia, infecting thousands of people worldwide.
Agudelo, Juliet   +10 more
core   +1 more source

SARS in Pregnancy

open access: yesAWHONN Lifelines, 2004
While severe acute respiratory syndrome (SARS) is increasing in prevalence throughout the world, there had not been a documented case of SARS in pregnancy until early 2003, when a pregnant woman infected with SARS sought care at this New Jersey Hospital in March 2003.
Johanna Gorab   +7 more
openaire   +3 more sources

A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

open access: yesNature Microbiology, 2020
The ongoing pandemic spread of a new human coronavirus, SARS-CoV-2, which is associated with severe pneumonia/disease (COVID-19), has resulted in the generation of tens of thousands of virus genome sequences.
A. Rambaut   +7 more
semanticscholar   +1 more source

Mechanisms of SARS-CoV-2 entry into cells

open access: yesNature reviews. Molecular cell biology, 2021
The unprecedented public health and economic impact of the COVID-19 pandemic caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been met with an equally unprecedented scientific response.
C. B. Jackson   +3 more
semanticscholar   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

open access: yes, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet   +10 more
core   +1 more source

Neurologic Features in Severe SARS-CoV-2 Infection

open access: yesNew England Journal of Medicine, 2020
Neurologic Features in SARS-CoV-2 Infection In a consecutive series of 64 patients with Covid-19 and ARDS, 58 of whom underwent neurologic examination, severe agitation and corticospinal signs were...
Julie Helms   +11 more
semanticscholar   +1 more source

Imaging in SARS [PDF]

open access: yesClinical Radiology, 2005
Meirion R. Evans BA(Hons), MB, BCh, FRCP, FFPHM Clinical Senior Lecturer Department of Epidemiology, Statistics & Public Health University of Wales College of Medicine Honorary Regional Epidemiologist PHLS Communicable Disease Surveillance Centre (Wales) Abton House, Wedal Road, Cardiff CF14 3QX United Kingdom Temporary Advisor on SARS, World Health ...
Anil T. Ahuja   +2 more
openaire   +5 more sources

Evolution of CDK1 Paralog Specializations in a Lineage With Fast Developing Planktonic Embryos

open access: yesFrontiers in Cell and Developmental Biology, 2022
The active site of the essential CDK1 kinase is generated by core structural elements, among which the PSTAIRE motif in the critical αC-helix, is universally conserved in the single CDK1 ortholog of all metazoans.
Xiaofei Ma   +5 more
doaj   +1 more source

In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

open access: yesClinical Infectious Diseases, 2020
Background The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) first broke out in Wuhan (China) and subsequently spread worldwide. Chloroquine has been sporadically used in treating SARS-CoV-2 infection.
Xueting Yao   +14 more
semanticscholar   +1 more source

Cell entry mechanisms of SARS-CoV-2

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance A key to curbing SARS-CoV-2 is to understand how it enters cells. SARS-CoV-2 and SARS-CoV both use human ACE2 as entry receptor and human proteases as entry activators.
J. Shang   +6 more
semanticscholar   +1 more source

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