Results 151 to 160 of about 378,875 (306)

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Isolation And Characterization Of The Precursor Virus Of Human Sars Virus: Sars-Associated Corona Virus-Like Virus

, 2011
published_or_final_version
openaire   +1 more source

ISOLATION AND CHARACTERIZATION OF THE PRECURSOR VIRUS OF HUMAN SARS VIRUS: SARS-ASSOCIATED CORONA VIRUS-LIKE VIRUS

, 2012
published_or_final_version
openaire   +1 more source

New human virus from SARS family

New Scientist, 2012
A virus never before seen in humans has infected two people, killing one. There is so far no evidence that it can spread readily between people.
openaire   +2 more sources

Cellular tropism and cell-to-cell fusion properties of the infectious bronchitis virus spike glycoprotein [PDF]

There are numerous vaccines available for the control of infectious bronchitis virus (IBV) in poultry, however protection is short-lived and poorly cross-protective between strains.
Bickerton, Erica Jane
core  

SARS virus in tears? [PDF]

The Lancet Infectious Diseases, 2004
openaire   +1 more source

Identification of individuals with gonorrhoea within sexual networks: a population-based study.

, 2006
BACKGROUND: Molecular typing of Neisseria gonorrhoeae and contact tracing provide a combined approach for analysis of sexual networks in metropolitan areas, although there are some difficulties in application.
Ison, Catherine A, Fenton, Kevin A, Spratt, Brian G, Risley, Claire L, Ghani, Azra C, Ward, Helen, Choudhury, Bhudipa, Bishop, Cynthia J   +7 more
core   +1 more source

Mortality and progression to AIDS after starting highly active antiretroviral therapy.

, 2003
OBJECTIVES: To examine survival and progression to AIDS among HIV-infected patients after starting highly active antiretroviral therapy (HAART). METHODS: The study population consisted of 3724 patients from the ATHENA observational cohort who initiated ...
de Wolf, Frank, Lange, JMA, van Sighem, A.I., Ghani, Azra C, Reiss, Peter, Lange, J.M.A., Lange, Joep MA, van de Wiel, Mark A, Sighem, van, A.I., Wolf, de, F., Gyssens, ICJ (Inge), Ghani, A.C., Ghani, AC, Gyssens, I.C., de Lange, J., van Sighem, Ard I, Gyssens, Inge C, Jambroes, M, Jambroes, M., Wiel, MA Mark van de, Wolf, F de, de Wolf, F, Brinkman, K., Wiel, van de, M.A., Sighem, AI van, Reiss, P, Sighem, AI, Brinkman, K, ATHENA Cohort Study Group, Jambroes, Mariëlle, Brinkman, Kees, de Wolf, F., Gyssens, IC, van de Wiel, M.A., van de Wiel, MA, Reiss, P.   +35 more
core   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source

Comparison of the risks of atherosclerotic events versus death from other causes associated with antiretroviral use.

, 2006
BACKGROUND: Studies considering the risk of atherosclerotic disease (AtD) associated with the use of HAART have reported inconsistent results. METHODS: Data on antiretroviral therapy (ART) use, risk factors for cardiovascular disease (CVD), AtD and death
de Wolf, Frank, Kwong, Grace PS, Ghani, Azra C, Cameron, D William, da Silva, Barbara, Cowling, Benjamin J., Danner, Sven A., Cameron, D. William, De Wolf, F, Ghani, AC, Anderson, RM, Bartley, Lucy M, van Sighem, Ard I, Bartley, LM, Kwong, GPS, Cowling, Benjamin J, Van Sighem, AI, Danner, SA, Donnelly, CA, Donnelly, Christl A., Ghani, Azra C., Anderson, Roy M, Danner, Sven A, Rode, Richard A, Rode, Richard A., Donnelly, Christl A, Da Silva, B, Bartley, Lucy M., Cowling, BJ, Cameron, DW, Van Sighem, Ard I., Rode, RA, Kwong, Grace P.S., Anderson, Roy M.   +33 more
core   +1 more source