Results 101 to 110 of about 1,600,173 (280)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
From Parallel SAT to Distributed SAT
EPiC Series in Computing, 2018 This tutorial will present an overview of parallelism in SAT. It will start with a presentation of classical divide and conquer techniques, discuss their ancient origin and compare them to more recent portfolio- based algorithms. It will then present the impact of clause-sharing on their performances and discuss various strategies used to control the ...
openaire +2 more sources
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
UNIVERSITIES AS GENERATOR FOR REGIONAL DEVELOPMENT
Высшее образование в России, 2016 Some systematic challenges for Russian higher education are considered. Several ways of meeting the challenges are proposed in order to turn regional universities into the centers of regional development.
Andrey V. Belotserkovsky
doaj
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
e-Kafkas Eğitim Araştırmaları DergisiThere is increasing evidence that cyber-ostracism adversely affects digital well-being, yet further research is needed to clarify the mechanisms underlying this relationship.
Mustafa Şat
doaj +1 more source
Conflict Analysis in Search Algorithms for Satisfiability
, 1996 This paper introduces GRASP (Generic search Algorithm jr the Satisfiabili{y Problem), a new search algorithm jr Propositional Satisfiabili{y (SAT). GRASP incorporates several search-pruning techniques, some of which are specific to SAT, whereas others ...
Marques-Silva, Joao, Sakallah, Karem
core +1 more source