Results 201 to 210 of about 138,192 (261)

Gridded millennial summer temperature dataset over the Yangtze River Basin. [PDF]

Sci Data
Dilawar A, Duan J, Liu Y, Babaeian I, Hosseini SA.   +4 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Physiological and Psychometric Assessment of a Multimodal e-Motion Training in Women. [PDF]

Healthcare (Basel)
Chellini A, Gerbi N, Schinco S, Iosa M, Morone G, Salera C.   +5 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The Multiscale Heterogeneity of Adipose Tissue in Health and Disease. [PDF]

Research (Wash D C)
Wang B, Jiang X, Wang Q, Xu A.
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Extremity Ultrasound vs. Computed Tomography at the Third Lumbar Vertebra Level for Assessing the Subcutaneous Adipose Tissue-to-Muscle Ratio. [PDF]

Nutrients
Fischer-Hammerschmied A, Pesta M, Hertwig A, Siebenrock T, Hahn R, Anwar M, Liebau K, Timmermann I, Brugger J, Posch M, Ringl H, Tamandl D, Veraar C, Lassnigg A, Bernardi M, Tschernko E, Jonckheer J, Sundström Rehal M, Hiesmayr M.   +18 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Adipose single cell epigenome and transcriptome localize genetic risk for cardiometabolic disease and accelerated aging. [PDF]

Nat Commun
Lee SHT, Kar A, Gelev KZ, Chen ZJ, Das SS, Heinonen S, Saarinen T, Vaittinen M, Kaminska D, Peltoniemi H, Luo C, Juuti A, Männistö V, Pihlajamäki J, Kaikkonen MU, Pietiläinen KH, Balliu B, Pajukanta P.   +17 more
europepmc   +1 more source