Results 211 to 220 of about 235,564 (296)

Adipose Tissue Expandability as a Link Between Nutrition and Obesity-Related Metabolic Risk: Insights from Bariatric Surgery. [PDF]

Nutrients
Jiménez-Flores E, Reytor-González C, Jima Gavilanes D, Rossetti G, Pilone V, Parrillo L, Cavallo M, Cobellis L, Simancas-Racines D, Schiavo L.   +9 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Depot-specific differences in visceral and subcutaneous adipose tissue from patients with obesity. [PDF]

Adipocyte
Neuhaus M, Fryklund C, Cai M, Fernø J, Mellgren G, Hagberg CE, Stenkula KG.   +6 more
europepmc   +1 more source

SAT-Accel: A Modern SAT Solver on a FPGA

Proceedings of the 2025 ACM/SIGDA International Symposium on Field Programmable Gate Arrays
Michael Lo, Mau-Chung Frank Chang, Jason Cong   +2 more
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Sediment accumulation rate predicts the temporal resolution of marine fossil assemblages. [PDF]

Proc Natl Acad Sci U S A
Kowalewski M, Tomašových A, Nawrot R, Scarponi D, Zuschin M, Albano PG, Hua Q, Kaufman DS, Kidwell SM, Ritter M, Simões MG, Torres L, Bachmann B, Berensmeier M, Dexter TA, Haselmair A, Gallmetzer I, Pellegrini C, Schweigl L, Steger J, Kosnik MA.   +20 more
europepmc   +1 more source

SAT-to-SAT: Declarative Extension of SAT Solvers with New Propagators

, 2020
Janhunen Tomi, Tasharrofi Shahab
openaire   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Culture-Negative Infective Endocarditis Presumed due to Brucella Causing Rapid Native Aortic Valve Destruction in a Young Adult: A Case Report. [PDF]

Clin Case Rep
Nassar B, Gharo KI, Ramahi O, Ghannam H, Romana A, Hashhash KA.   +5 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source