Results 221 to 230 of about 1,605,280 (279)

How effective is rejoining a long-term weight loss program? The 5- and 10-year MRI-assessed Follow Interventions Trial (FIT) project. [PDF]

BMC Med
Klein H, Pachter D, Goldberg Toren DT, Kamer O, Alufer L, Ebstein Karamani N, Chassidim Y, Shelef I, Rudich A, Yoel U, Ben-Arie G, Zelicha H, Yaskolka Meir A, Tsaban G, Bartal C, Blüher M, Stumvoll M, Ceglarek U, Isermann B, Qi L, Stampfer MJ, Hu FB, Shai I.   +22 more
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Serum metabolite patterns of adipose tissue distribution and body composition subphenotypes. [PDF]

Lipids Health Dis
Maushagen J, Grune E, Schlett CL, Kiefer LS, Suhre K, Adamski J, Wang-Sattler R, Peters A, Bamberg F, Rospleszcz S.   +9 more
europepmc   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

[Analysis of the Advantages and Clinical Validation of Real-Time Fluorescence Nucleic Acid Isothermal Amplification Detection Technology in Detecting Low Viral Load Samples From HBV-Infected Patients]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Huang Q, Xie R, Lan Y, Xun Z, Ou Q, Liu C.   +5 more
europepmc   +1 more source

Integrated targeted metabolomics and transcriptomics analysis reveals heterogeneity of subcutaneous and pericardial adipose tissues in Yili horses. [PDF]

Food Chem (Oxf)
Yang L, Shen Z, Song L, Lu Z, Zeng Y, Wang J, Ren W, Yao X, Meng J.   +8 more
europepmc   +1 more source

The progression of TRAb-positive subacute thyroiditis and its differential diagnosis from Graves' disease. [PDF]

Front Immunol
Yuan S, Zhao X, Liu F, Yao J, Zhao J.
europepmc   +1 more source

NCOA1 is a gatekeeper of the sexually dimorphic thermogenic activity of white adipose tissue. [PDF]

Nat Commun
Tannour-Louet M, Pisani DF, Bouguerra H, Zedda A, Bourcier M, Lamghari N, Gautier N, Chaput B, Riant E, Bouloumié A, Montastier E, Viguerie N, Langin D, Amri EZ, Gourdy P, Tanti JF, Cormont M, Louet JF.   +17 more
europepmc   +1 more source

Sieving for gold: external comparator studies to prioritize drugs for late-stage clinical trial. [PDF]

J Comp Eff Res
Vennin S, Sopwith W, Calvo E, Cantoni C, Del Valle PC, Maissenhaelter B, Rippin G, Ryll B, Osterwalder B.   +8 more
europepmc   +1 more source

Distinct precursor landscape of subcutaneous and visceral fat in development and aging. [PDF]

Cell Rep
Lin F, Sul HS.
europepmc   +1 more source