Results 151 to 160 of about 716,844 (310)

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Satellite SAR wind resource mapping in China (SAR-China) [PDF]

open access: yes, 2009
The project ‘Off-Shore Wind Energy Resource Assessment and Feasibility Study of Off-Shore Wind Farm Development in China’ is funded by the EU-China Energy and Environment Programme (EEP) and runs for one year (August 2008 - August 2009). The project is lead by the China Meteorological Administration (CMA) and supported by SgurrEnergy Ltd. Risø National
openaire  

On the analyzing of bifurcation properties of the one‐dimensional Mackey–Glass model by using a generalized approach

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
The goal of this work is to look at how a nonlinear model describes hematopoiesis and its complexities utilizing commonly used techniques with historical and material links. Based on time delay, the Mackey–Glass model is explored in two instances. To offer a range, the relevance of the parameter impacting stability (bifurcation) is recorded.
Shuai Zhang   +5 more
wiley   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

open access: yesNeuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji   +4 more
wiley   +1 more source

TanDEM-X Mission Status [PDF]

open access: yes, 2011
TanDEM-X (TerraSAR-X add-on for Digital Elevation Measurement) opens a new era in spaceborne radar remote sensing [1]. A single-pass SAR interferometer with adjustable baselines in across- and in along-track directions is formed by adding a second (TDX),
Schulze, Daniel   +4 more
core  

Efficacy of Endoscopic Sinus Surgery for Allergic Fungal Rhinosinusitis: A Systematic Review With Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Endoscopic sinus surgery (ESS) plays a central role in the management of allergic fungal rhinosinusitis (AFRS); however, outcomes vary across studies. The goal of this study is to systematically review and synthesize evidence on the outcomes of ESS in patients with AFRS.
Amani Kais   +4 more
wiley   +1 more source

A reconstructed Pangea would result in lower biodiversity

open access: yesOikos, EarlyView.
Driven by globalization and climatic change, rates of biological invasion are on the increase. Although these increasing rates are widely expected to lead to increased rates of extinction, it has been argued that these ‘newly arrived' species might increase biodiversity.
John M. Halley, Gábor L. Lövei
wiley   +1 more source

Globalizing Comparative Public Administration With Integrative Contextualization: State Autonomy in the Developmental Path of Hong Kong and Singapore

open access: yesPublic Administration and Development, EarlyView.
ABSTRACT The lack of a common variable for comparison has been a major obstacle to the development of Comparative Public Administration (CPA). State autonomy enables an integrative contextualization approach, allowing both the analysis of contextual individual country experiences and the generation of generalized comparable knowledge.
Wilson Wong
wiley   +1 more source

Muscle fatigue in patients with severe long COVID: A 2‐year follow‐up study

open access: yesPM&R, EarlyView.
Abstract Background Fatigue is recognized as one of the most persistent and debilitating symptoms of long COVID, affecting both functionality and quality of life. However, its long‐term effects, especially beyond the first year after infection, remain poorly understood.
Isabella da Silva Almeida   +6 more
wiley   +1 more source

Infrastructure monitoring by satellite SAR

open access: yesArtificial Intelligence and Data Science, 2023
openaire   +1 more source

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