Results 41 to 50 of about 955,972 (287)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Experimental Study on Anisotropic Strength and Deformation Behavior of a Coal Measure Shale under Room Dried and Water Saturated Conditions

open access: yesShock and Vibration, 2015
This paper presents an experimental investigation of anisotropic strength and deformation behavior of coal measure shale. The effect of two factors (i.e., anisotropy and water content) on shale strength and deformation behavior was studied.
Jingyi Cheng   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Acknowledgment to Reviewers of Designs in 2020

open access: yes, 2021
Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Designs maintains its standards for the high quality of its published papers [...
Designs Editorial Office Designs Editorial Office
core   +1 more source

Analysis on influencing factors of heat transfer characteristics of vertical borehole heat exchanger under stratified soil conditions

open access: yesCase Studies in Thermal Engineering, 2023
In recent years, factors influencing the heat transfer characteristics of the vertical borehole heat exchanger (BHE) is a hot topic in the research of the ground source heat pump (GSHP) systems. Given the complexities involved in environmental situations
Songqing Wang   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Optimizing dissolved air flotation design and saturation

open access: yesWater Science and Technology, 2001
Dissolved air flotation (DAF) of iron hydroxide precipitates at working pressures lower than 3 atm, using modified flotation units to improve the collection of fragile coagula, was studied. Conventional DAF flotation was studied as a function of saturation pressure in the absence and presence of surfactants in the saturator.
L A, Féris   +3 more
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Two-Level Optical Coherence Tomography Scheme for Suppressing Spectral Saturation Artifacts

open access: yesSensors, 2014
We demonstrate a novel method for reducing saturation artifacts in spectral-domain optical coherence tomography (SD-OCT) systems. This method is based on a two-level SD-OCT system with a dual-line charge-coupled device (CCD) camera.
Chiung-Ting Wu   +2 more
doaj   +1 more source

The general Nature of Saturated Designs

open access: yes, 2019
We contemplate an experimental situation in a $2^k$-factorial experiment with acute resource crunch so that we need to conduct just a saturated design [SD] - with the understanding that precision of the estimates cannot be estimated from the data. It is known beforehand which effect(s)/interaction(s) are likely to be negligible.
Domagni, Francois   +2 more
openaire   +2 more sources

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