Results 151 to 160 of about 115,822 (353)

Piperazine‐Functionalized Nanoparticles Enable Oral Insulin Delivery in Obese Mice

open access: yesAdvanced Science, EarlyView.
ABSTRACT Biologics have gained prominence as a rapidly advancing therapeutic modality for a diverse spectrum of medical conditions. Nonetheless, they are predominantly administered parenterally due to poor absorption through the gastrointestinal tract. Additionally, repeated injections of biologics such as insulin cause injection pain, leading to dose ...
Yuxue Cao   +14 more
wiley   +1 more source

Skin‐Inspired Design of Self‐Healing Coatings Integrating Interface‐Liquid Repellency and Corrosion Resistance

open access: yesAdvanced Science, EarlyView.
A skin‐inspired multilayered coating system is developed to integrate multiple, often conflicting, functions of self‐healing capability, strong liquid repellency, long‐term corrosion resistance, and robust adhesion, to tackle diverse challenges in engineering services.
Bingzhi Li   +8 more
wiley   +1 more source

Small Grain Forage Trial Nitrogen Fertility and Harvest Date [PDF]

open access: yes, 2012
Cool season annual forages, such as cereal grains, can provide early season grazing as well as high quality stored feed. However, it is unclear if quality and yield of these forages could be improved through better fertility management.
Cummings, Erica   +4 more
core   +1 more source

Rapid Proteome‐Wide Discovery of Protein–Protein Interactions With ppIRIS

open access: yesAdvanced Science, EarlyView.
ppIRIS is a lightweight deep learning framework for proteome‐wide protein–protein interaction prediction directly from sequence. By fusing evolutionary and structural embeddings with a regularized Siamese architecture, ppIRIS achieves state‐of‐the‐art accuracy across species, enables minute‐scale screening, and reveals biologically validated bacterial ...
Luiz Felipe Piochi   +4 more
wiley   +1 more source

A Simple Polarization for Powerful Preliminary Test of Oil Quality Level [PDF]

open access: yes, 2015
In this paper, light polarization has been used to indicate level quality of various vegetable oils. A new indication of level quality used here was change of light polarization, and was measured using a simple pair of polarizer-analyzer.
Firdausi, K. Sofjan   +3 more
core  

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

open access: yesAdvanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin   +9 more
wiley   +1 more source

An Assessment of the Potential Consumption Impacts of WHO Dietary Norms in OECD Countries [PDF]

open access: yes
The member countries of the World Health Organization (WHO) have recently endorsed its Global Strategy on Diet, Physical Activity and Health. The strategy emphasizes the need to limit the consumption of saturated fats and trans fatty acids, salt and ...
Irz, Xavier T.   +2 more
core   +1 more source

Saturated fat in an evolutionary context

open access: yesLipids in Health and Disease
Evolutionary perspectives have yielded profound insights in health and medical sciences. A fundamental recognition is that modern diet and lifestyle practices are mismatched with the human physiological constitution, shaped over eons in response to environmental selective pressures.
openaire   +3 more sources

GPX4 Inhibitor Resistance and Metastatic Features in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes breast cancer cell lines that are resistant to glutathione peroxidase 4 inhibitors (GPX4i) in vitro and investigates the metastatic capacity of the GPX4i‐resistant versus parental lines in vivo. GPX4i‐resistant cells survive upon intravenous injection, but lose capacity to spontaneously metastasize.
Marie Sabatier   +16 more
wiley   +1 more source

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