Results 31 to 40 of about 3,303,901 (256)

The importance of the sampling design in mapping woody cover in arid ecosystems

GIScience & Remote Sensing
Accurate calibration data remains a major constraint in ecological remote sensing, particularly in arid ecosystems where sparse and heterogeneous woody vegetation is challenging to detect.
Felana Nantenaina Ramalason, Olivia Lovanirina Rakotondrasoa, Arthur Vander Linden, Guillaume Renard, Josoa R. Randriamalala, Nicolas J. Vereecken, Aina Razakamiaramanana, Mbolatiana F. Ranaivoharivelo, Sismondi Raholinarivo, Harifidy Rakoto Ratsimba, Jan Bogaert, Jean-François Bastin   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Exact D-optimal designs of experiments for linear multiple regression with heteroscedastic observations

Журнал Белорусского государственного университета: Математика, информатика, 2018
In article the problem of construction of exact D-optimal designs of experiments for linear multiple regression in a case when variance of errors of observations depend on a point in which is made is investigated. The class functions describing change of
Valery P. Kirlitsa
doaj  

Optimizing the Composition of Fiber-Reinforced Concrete Airfield Pavements to Improve Performance and Prevent Cracking

Structural Mechanics of Engineering Constructions and Buildings
Concrete airfield pavements often experience premature failure due to extensive cracking under repeated loading and environmental exposure. Traditional single-scale fiber reinforcement methods have proven inadequate in controlling both micro- and macro ...
Qais A.A. Qais, Galina E. Okolnikova, Serdar B. Yazyev, Mahmoud A. A. Obeid   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Comparative analysis of saturated–unsaturated shear strength under undrained loading: Experimental validation and ANN prediction of clayey soils

AIP Advances
Geotechnical designs and analyses of earth structures and foundations exclusively involve the assessment and consideration of unsaturated soil shear strength. The laboratory testing equipment and methods for predicting the unsaturated soil shear strength
Prashant Pande, Jayant Giri, Mohd Sajid Ali, Faruq Mohammad, Jayant Raut, Sanjay Raut, T. Sathish, Pallavi Giri   +7 more
doaj   +1 more source

Distributed Control Scheme for the Coordination of Interlinking Converters in Islanded Hybrid AC/DC Multi-Microgrids

IEEE Open Journal of the Industrial Electronics Society
Multiple interconnected ac and dc microgrids (MGs) are being studied by academia and industry because of their benefits despite their operational challenges.
Manuel Martinez-Gomez, Marcos E. Orchard, Serhiy Bozhko, Patrick Wheeler, Claudio Burgos-Mellado   +4 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

D-optimal designs for Poisson regression models [PDF]

, 2008
We consider the problem of finding an optimal design under a Poisson regression model with a log link, any number of independent variables and an additive linear predictor.
Lewis, S. M., Woods, D. C., Eccleston, J. A., Woods, D.C., Eccleston, J.A., Lewis, S.M., Russell, K.G., Russell, K. G.   +7 more
core   +1 more source