Results 31 to 40 of about 3,364,057 (201)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
Analysis of Saturation Flow at Signalized Intersections [PDF]
, 1982 The accuracy of saturation flow values is of prime importance when determining the capacity of signalized intersections. The objective of this study was to collect a large sample of field measurements so that reliable saturation flow values could be ...
Crabtree, Joseph D., Agent, Kenneth R.
core +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Passenger Car Equivalent Estimation Methods at Urban Signalized Intersections: A Systematic Review
Future TransportationThis study presents a systematic review of Passenger Car Equivalency (PCE) at signalized intersections. The review focuses on comparing PCE calculation methods, examining PCE values across methods, and identifying the key influencing factors.
Sevinç Özgün, Kemal Selçuk Öğüt
doaj +1 more source
Estimation of saturation flow rates on dual left-turn lanes [PDF]
Tehnika, 2018 Signalized intersection capacity estimation and signal timing parameters optimization are directly related to the term 'saturation flow'. This parameter was the subject of numerous studies in which base saturation flow rates and its impact factors were ...
Kocić Anica M. +3 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Modelling the saturation flow rate for continuous flow intersections based on field collected data.
PLoS ONE, 2020 The continuous flow intersection [CFI) is an unconventional intersection design which has been used in many cities all over the world. However, as an important parameter for the geometric design, signal timing, and operation evaluation, the saturation ...
Xing Gao, Jing Zhao, Meng Wang
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source