Results 71 to 80 of about 36,674 (213)

An X‐ray and γ‐ray combination strategy to exploit steep dose gradients for improved prostate cancer radiotherapy: A dosimetric comparison of Taichi Pro and Halcyon

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose This study aimed to evaluate a novel technological platform, Taichi Pro—which integrates a 6 MV flattening filterfree linear accelerator with a 18 source Rotating Gamma System (RGS) to generate steep dose gradients via multisource focused γ‐rays and noncoplanar arcs—for precision radiotherapy in prostate cancer.
Kuo Li, Yong Yin, Ting Zhu, Weipeng Sun, Shihao Wang, Zhenjiang Li   +5 more
wiley   +1 more source

Commissioning and validation of the Elekta One GPUMCD algorithm for an Elekta VersaHD linear accelerator

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Purpose The purpose of this work was to commission and validate GPUMCD, a GPU‐accelerated Monte Carlo dose calculation engine for c‐arm Elekta linear accelerators (linac). This algorithm was recently released for clinical implementation in the Elekta One Treatment Planning System (v6.2.3, EOP). Methods A GPUMCD beam model was generated for all
Samuel D. Rusu, Blake R. Smith, Grace H. Hutchinson, Jun Hsuang Jen, Daniel E. Hyer   +4 more
wiley   +1 more source

Prognosis and Risk Factors of Radiation-Induced Lymphopenia in Early-Stage Lung Cancer Treated With Stereotactic Body Radiation Therapy

Frontiers in Oncology, 2020
Background: To investigate the role of stereotactic body RT (SBRT) in decreased total peripheral lymphocyte count (TLC) in patients with early-stage lung cancer and to explore possible risk factors for RT-induced lymphopenia.Materials and Methods: We ...
Qianqian Zhao, Tingting Li, Gang Chen, Zhaochong Zeng, Jian He   +4 more
doaj   +1 more source

Impact of Monaco sequencing parameters on monitor units, plan quality, and optimization time for Elekta Unity liver SBRT plans

Journal of Applied Clinical Medical Physics, Volume 27, Issue 3, March 2026.
Abstract Background Magnetic resonance‐guided radiation therapy (MRgRT) using the Elekta Unity MR‐linac offers significant advantages for liver stereotactic body radiation therapy (SBRT). However, the Unity is limited by a low dose rate and the lack of volumetric‐modulated arc therapy (VMAT), resulting in prolonged treatment times.
Bryan C. Bates, Guanghua Yan, Amanda Schwarz   +2 more
wiley   +1 more source

Influence of respiratory motion management technique on radiation pneumonitis risk with robotic stereotactic body radiation therapy. [PDF]

, 2018
Purpose/objectivesFor lung stereotactic body radiation therapy (SBRT), real-time tumor tracking (RTT) allows for less radiation to normal lung compared to the internal target volume (ITV) method of respiratory motion management. To quantify the advantage
Bahig, Baker, Barriger, Benedict, Bibault, Borst, Braunstein, Brown, Chang, Depuydt, Descovich, Fowler, Gibbs, Gopal, Guckenberger, Harder, Hoogeman, Jung, Keall, Kim, Movsas, Onishi, Ricardi, Seppenwoolde, Shah, Thariat, Trumm, Tsoutsou, Videtic, Wang, Wennberg, Withers, Yamashita   +32 more
core   +2 more sources

Engineered Bacteria‐Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity

Advanced Science, Volume 13, Issue 16, 18 March 2026.
We engineered a bacterial‐vesicular dual‐delivery platform that targets LOx to colorectal tumors, enabling lactate clearance, immune microenvironment remodeling, and microbiota modulation. This microbe–metabolism synergistic strategy effectively sensitizes colorectal cancer to radiotherapy, offering a promising approach to overcome radioresistance ...
Fei Peng, Zhe Lei, Zhehao Zhang, Zhiyue Su, Chonghai Zhang, Huan Yang, Shu Liu, Mengyuan Hu, Yuhong Wang, Lingchuan Guo, Lin Hu, Kai Yang   +11 more
wiley   +1 more source

Repurposing metformin for cancer treatment: current clinical studies. [PDF]

, 2016
In recent years, several studies have presented evidence suggesting a potential role for metformin in anti-cancer therapy. Preclinical studies have demonstrated several anticancer molecular mechanisms of metformin including mTOR inhibition, cytotoxic ...
Altman, Jessica K, Arya, Ayush, Carneiro, Benedito, Chae, Young Kwang, Chandra, Sunandana, Giles, Francis, Kalyan, Aparna, Kaplan, Jason, Malecek, Mary-Kate, Platanias, Leonidas, Shin, Daniel Sanghoon   +10 more
core   +1 more source

Repeat stereotactic body radiotherapy (SBRT) for local recurrence of non-small cell lung cancer and lung metastasis after first SBRT

Radiation Oncology, 2018
Background This study evaluated the safety and efficacy of repeat SBRT for local recurrence of stage I non-small-cell lung cancer (NSCLC) and solitary lung metastasis.
Yasutaka Ogawa, Yuta Shibamoto, Chisa Hashizume, Takuhito Kondo, Hiromitsu Iwata, Natsuo Tomita, Hiroyuki Ogino   +6 more
doaj   +1 more source

Magnetic Resonance Guided Radiation Therapy (MRgRT) Prostate Motion and Margins

Journal of Medical Radiation Sciences, Volume 73, Issue 1, Page 44-51, March 2026.
This study evaluated intra‐fractional prostate motion during MR‐guided radiotherapy to determine appropriate PTV margins for prostate cancer. Analysis of 18 patients resulted in calculated margins of 3.2 mm (AP), 1.7 mm (LR), and 3.2 mm (SI), supporting the potential for margin reduction with MRgRT. ABSTRACT Introduction Systematic and random errors in
Sammi Peng, Tegan Courtot, Jessica Lye, Farshad Foroudi, Mark Tacey, Daryl Lim Joon, Michael Chao, Ee Siang Choong   +7 more
wiley   +1 more source

Outcomes Following Stereotactic Body Radiotherapy with Intensity-Modulated Therapy versus Three-Dimensional Conformal Radiotherapy in Early Stage Non-Small Cell Lung Cancer

Lung Cancer: Targets and Therapy, 2019
Michael Mix,1 Sean Tanny,1 Tamara Nsouli,1 Ryan Alden,1 Rishabh Chaudhari,2 Russell Kincaid,1 Paula F Rosenbaum,3 Jeffrey A Bogart,1 Paul Aridgides1 1Department of Radiation Oncology, SUNY Upstate Medical University, Syracuse, NY 13210, USA; 2Department ...
Mix M, Tanny S, Nsouli T, Alden R, Chaudhari R, Kincaid R, Rosenbaum PF, Bogart JA, Aridgides P   +8 more
doaj