Results 71 to 80 of about 42,868 (258)

Efficacy and acquired resistance for EGFR-TKI plus thoracic SBRT in patients with advanced EGFR-mutant non–small-cell lung cancer: a propensity-matched retrospective study

BMC Cancer, 2021
Background This retrospective study aimed to evaluate the efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) with stereotactic body radiation therapy (SBRT) and to elucidate potential mechanisms of acquired resistance ...
Xia Wang, Zhimin Zeng, Jing Cai, Peng Xu, Pingan Liang, Yuxi Luo, Anwen Liu   +6 more
doaj   +1 more source

Stereotactic MRI-guided Adaptive Radiation Therapy (SMART) for Locally Advanced Pancreatic Cancer: A Promising Approach. [PDF]

, 2018
Locally advanced pancreatic cancer (LAPC) is characterized by poor prognosis and low response durability with standard-of-care chemotherapy or chemoradiotherapy treatment.
Cao, Minsong, Lamb, James, Lee, Percy, Low, Daniel A, Luterstein, Elaine, Raldow, Ann C, Steinberg, Michael L   +6 more
core   +1 more source

Multi‐omics predicts radiotherapy response in small cell lung cancer patients receiving whole brain irradiation

Journal of Applied Clinical Medical Physics, Volume 27, Issue 2, February 2026.
Abstract Objective Dosiomics and radiomics elaborate the low‐and high‐order features extracted from images to predict clinical outcomes. Whole‐brain radiotherapy (WBRT) has been widely used in patients with diffuse brain metastases of small cell lung cancer (SCLC).
Yifan Lei, Han Bai, Chengshu Gong, Yaoxiong Xia, Yu Hou, Ruiling Yang, Jinhui Yu, Zhe Zhang, Li Wang, Bo Li, Li Wang, Lan Li   +11 more
wiley   +1 more source

A Flexible Implementation of a Matrix Laurent Series-Based 16-Point Fast Fourier and Hartley Transforms [PDF]

, 2015
This paper describes a flexible architecture for implementing a new fast computation of the discrete Fourier and Hartley transforms, which is based on a matrix Laurent series. The device calculates the transforms based on a single bit selection operator.
de Oliveira, H. M., de Oliveira, R. C., de Souza, R. M. Campello, Santos, E. J. P.   +3 more
core   +1 more source

Impact of Prior Treatment History on Recurrence After Complete Response to Atezolizumab Plus Bevacizumab in Unresectable Hepatocellular Carcinoma

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Aim Integration of locoregional treatments (LRTs) with atezolizumab plus bevacizumab (atezo/bev) has improved treatment outcomes, enabling an increasing number of patients with unresectable hepatocellular carcinoma (HCC) to achieve a complete response (CR). A comprehensive analysis of recurrence following CR may provide insights into prognosis.
Tasuku Nakabori, Masaki Kawabata, Kaori Mukai, Hidenari Hongyo, Noboru Maeda, Makiko Urabe, Yugo Kai, Ryoji Takada, Kenji Ikezawa, Hiroshi Wada, Kunihito Gotoh, Kazuyoshi Ohkawa   +11 more
wiley   +1 more source

Repeat stereotactic body radiotherapy (SBRT) for local recurrence of non-small cell lung cancer and lung metastasis after first SBRT

Radiation Oncology, 2018
Background This study evaluated the safety and efficacy of repeat SBRT for local recurrence of stage I non-small-cell lung cancer (NSCLC) and solitary lung metastasis.
Yasutaka Ogawa, Yuta Shibamoto, Chisa Hashizume, Takuhito Kondo, Hiromitsu Iwata, Natsuo Tomita, Hiroyuki Ogino   +6 more
doaj   +1 more source

Hepatocellular carcinoma and multidrug resistance: Past, present and new challenges for therapy improvement [PDF]

, 2015
Hepatocellular carcinoma (HCC) is the most common malignancy of the liver and the third cause of cancer death worldwide. Chronic hepatitis due to HBV and HCV infection are two major risk factors for HCC worldwide.
Cuestas, María Luján, Mathet, Veronica Lidia, Oubiña, Jose Raul   +2 more
core   +1 more source

Assessing Quality and Adherence to PI‐RADSv2.1 Minimum Technical Standards of Prostate MRI in NRG‐GU005

Journal of Magnetic Resonance Imaging, Volume 63, Issue 2, Page 464-474, February 2026.
ABSTRACT Background Multi‐parametric MRI (mpMRI) datasets often vary between sites due to differences in acquisition protocols. Purpose Evaluate adherence of multi‐site mpMRI dataset to minimum technical standards (MTS) of PI‐RADSv2.1. Study Type Prospective.
Stephanie Alley, Marion Tonneau, Damien Olivié, Clare M. Tempany‐Afdhal, Peter L. Choyke, I. Baris Turkbey, Uulke A. van der Heide, Rodney J. Ellis, Samuel Kadoury, Thomas P. Boike, J. Daniel Pennington, Arthur Frazier, Colleen A. F. Lawton, Nelson Leong, Alina M. Mihai, Scott C. Morgan, Abhishek A. Solanki, Jeff M. Michalski, Felix Y. Feng, Howard M. Sandler, Cynthia Menard   +20 more
wiley   +1 more source

A tandem reinforcement learning framework for localized prostate cancer treatment planning and machine parameter optimization

Medical Physics, Volume 53, Issue 2, February 2026.
Abstract Background Volumetric modulated arc therapy (VMAT) machine parameter optimization (MPO) is a complex, high‐dimensional problem typically solved with inverse planning solutions that are both temporally and computationally expensive. While machine learning techniques have been explored to automate this process, they often supplement rather than ...
Nathan Shaffer, Avinash Reddy Mudireddy, Joel St‐Aubin   +2 more
wiley   +1 more source

Organ‐specific equivalent uniform dose constraints and radiobiological parameters for radiation treatment planning of abdominal tumors

Journal of Applied Clinical Medical Physics, Volume 27, Issue 1, January 2026.
Abstract Background Radiation therapy planning (RTP) for abdominal tumors often requires multiple dose‐volume constraints for each organ at risk (OAR), which vary with different fractionation schemes. This variability can complicate biologically optimized treatment planning.
Samira Dabaghmanesh, X. Allen Li, Eric S. Paulson, Beth Erickson, William Hall, An Tai   +5 more
wiley   +1 more source