Results 131 to 140 of about 52,126 (308)
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
The Organic Research Centre - Elm Farm:Bulletin 87 [PDF]
, 2007 Bulletin 87 with coverage of Avian Influenza H5N1 in Suffolk,commentary on Biofuels, a paper on the organic "transition to sustainable resilience",paper on participatory approach to agronomy trials,update on evolutionary breeding of wheat project,article
Fleming, D +5 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
TARGET CHARACTER’S COLLECTIONS OF APPLE-TREE AND PEAR-TREE IN BELARUS [PDF]
Fruit Growing Research, 2014 At the Institute for Fruit Growing in Belarus historically, much attention is paid to fruit breeding, particularly to apple and pear. The basis for the creation of the Belarusian varieties of new generation is National apple (1,264 accessions) and pear ...
Zoya Kazlouskaya +3 more
doaj
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Field efficacy of new compounds to replace copper for scab control in organic apple production [PDF]
, 2007 Efficacy of compounds was investigated in field experiments in Denmark and the Netherlands according to EPPO guidelines. Some Yucca extracts and potassium bicarbonate had an efficacy similar to sulphur on leaves.
Bengtsson, M. +5 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Investigations on alternative substances for control of apple scab - results from sanitation trials [PDF]
, 2004 The intention of this research project, which was supported within the "Bundesprogramm Ökologischer Landbau", was to look for alternatives in organic fruit growing to control apple scab, Venturia inaequalis. One important part of the investigations was
A., Kollar +5 more
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