Results 141 to 150 of about 3,473,693 (329)

Annual report 2002 LBI organic fruit growing research [PDF]

open access: yes, 2002
Overview of projects, project results, funding bodies and partners in 2002 and plans for 2003 Including: SOIL MANAGEMENT * Evaluation of leaf analysis in organic fruit growing as a tool for measuring the uptake of nutrients: Consultants and ...
Bloksma, Joke   +2 more
core  

Acceptability of scab-resistant apple cultivars

open access: yes, 2015
Apple scab, caused by the fungus Venturia Inaequalis, is one of the most important apple disease. A possible solution to contrast the increasing virulence of this fungus fostered by the lack of effective chemical molecules with low environmental impact lies in the introduction of scab-resistant plants. Some new varieties, combining scab resistance with
Endrizzi, Isabella   +5 more
openaire   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Fruit quality of Elstar en Santana in the Netherlands [PDF]

open access: yes, 2004
The growth of the market for Dutch organic apples is disappointing. Especially the large-scale introduction in the supermarket channel is not happening as fast as many hoped.
Jansonius, Pieter Jans
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Development of a hybrid apple population: MAS-based testing for Vf gene detection and preliminary field evaluation of its scab resistance

open access: yesHorticultural Science
The apple scab, caused by Venturia inaequalis, is one of the most devastating diseases of apples because it drastically affects the aerial parts of the tree. Apple breeding programs frequently aim to develop cultivars exhibiting resistance to scab. Thus,
Georgeta Maria Guzu   +6 more
doaj   +1 more source

Field efficacy of new compounds to replace copper for scab control in organic apple production [PDF]

open access: yes, 2007
Efficacy of compounds was investigated in field experiments in Denmark and the Netherlands according to EPPO guidelines. Some Yucca extracts and potassium bicarbonate had an efficacy similar to sulphur on leaves.
Bengtsson, M.   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

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