Results 71 to 80 of about 3,473,693 (329)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Prospecting for organic fungicides and resistance inducers to control scab (Venturia inaequalis) in organic apple production [PDF]

open access: yes, 2006
As a part of the REPCO project we are prospecting for plant extracts and other materials to control apple scab in order to find substitutes for copper fungicides in organic apple production.
Bengtsson, Marianne   +3 more
core  

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman   +7 more
wiley   +1 more source

Resistance Breeding in Apple at Dresden-Pillnitz [PDF]

open access: yes, 2008
Resistance breeding in apple has a long tradition at the Institute of Fruit Breeding now Julius Kuehn-institute in Dresden-Pillnitz. The breeding was aimed at the production of multiple resistance cultivars to allow a more sustainable and environmentally
Dunemann, F.   +6 more
core  

Cisgenesis, a new tool for traditional plant breeding, should be exempted from the regulation on genetically modified organisms in a step by step approach [PDF]

open access: yes, 2008
Modern potato breeding requires over 100,000 seedlings per new variety. Main reasons are (1) the increasing number of traits that have to be combined in this tetraploid vegetatively propagated crop, and (2) an increasing number of traits (e.g ...
Jacobsen, E., Schouten, H.J.
core   +2 more sources

Genetic Resistance to Scab Disease in Pecan [PDF]

open access: yesHortScience, 1994
Thirty-six cultivars and 948 seedlings from 15 controlled crosses in the U.S. Dept. of Agriculture-Agricultural Research Service pecan [Carya illinoinensis (Wangenh.) K. Koch] breeding program at Brownwood, Texas, were rated for susceptibility to nut scab [Cladosporium caryigenum (Ell.
Tommy E. Thompson, L.J. Grauke
openaire   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Highly scab-resistant transgenic apple lines achieved by introgression of HcrVf2 controlled by different native promoter lengths [PDF]

open access: yes, 2018
Apple scab, caused by the ascomycete Venturia inaequalis, is the most damaging fungal disease of commercial apple orchards. Functional scab resistance genes are present in some wild Malus species.
Broggini, Giovanni   +7 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Determining The Effect of Mass Selection for FHB Resistance in Soft Red Winter Wheat Using an Image-Based Optical Sorter

open access: yesAl-Qadisiyah Journal For Agriculture Sciences, 2019
Fusarium head blight (FHB) or head scab, caused by Fusarium graminearum Schwabe [telomorph: Gibberella zeae Schwein.(Petch)], is one of the most destructive diseases of wheat (Triticum aestivum L.) worldwide.
Hussein M. Khaeim   +3 more
doaj   +1 more source

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