Results 141 to 150 of about 954,074 (407)

Validation of an in vitro 3D bone culture model with perfused and mechanically stressed ceramic scaffold [PDF]

open access: yesEuropean Cells & Materials, 2015
An engineered three dimensional (3D) in vitro cell culture system was designed with the goal of inducing and controlling in vitro osteogenesis in a reproducible manner under conditions more similar to the in vivo bone microenvironment than traditional ...
G Bouet   +5 more
doaj  

Heterogeneous porous scaffold generation in trivariate B-spline solid with triply periodic minimal surface in the parametric domain [PDF]

open access: yesarXiv, 2019
A porous scaffold is a three-dimensional network structure composed of a large number of pores, and triply periodic minimal surfaces (TPMSs) are one of conventional tools for designing porous scaffolds. However, discontinuity, incompleteness, and high storage space requirements are the three main shortcomings of TPMSs for porous scaffold design.
arxiv  

Macrophage-Driven Biomaterial Degradation Depends on Scaffold Microarchitecture

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
In situ tissue engineering is a technology in which non-cellular biomaterial scaffolds are implanted in order to induce local regeneration of replaced or damaged tissues.
T. Wissing   +7 more
semanticscholar   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

GelMA synthesis and sources comparison for 3D multimaterial bioprinting

open access: yesFrontiers in Bioengineering and Biotechnology
Gelatin Methacryloyl (GelMA) is one of the most used biomaterials for a wide range of applications, such as drug delivery, disease modeling and tissue regeneration. GelMA is obtained from gelatin, which can be derived from different sources (e.g., bovine
Cesare Gabriele Gaglio   +5 more
doaj   +1 more source

Engineering thick tissues - the vascularisation problem [PDF]

open access: yesEuropean Cells & Materials, 2007
The ability to create thick tissues is a major tissue engineering challenge, requiring the development of a suitable vascular supply. Current trends are seeing the utilization of cells seeded into hybrid matrix/scaffold systems to create in vitro ...
H C H Ko, B K Milthorpe, C D McFarland
doaj  

ScaffoldNet: Detecting and Classifying Biomedical Polymer-Based Scaffolds via a Convolutional Neural Network [PDF]

open access: yesarXiv, 2018
We developed a Convolutional Neural Network model to identify and classify Airbrushed (alternatively known as Blow-spun), Electrospun and Steel Wire scaffolds. Our model ScaffoldNet is a 6-layer Convolutional Neural Network trained and tested on 3,043 images of Airbrushed, Electrospun and Steel Wire scaffolds.
arxiv  

3D- Printed Poly(ε-caprolactone) Scaffold Integrated with Cell-laden Chitosan Hydrogels for Bone Tissue Engineering

open access: yesScientific Reports, 2017
Synthetic polymeric scaffolds are commonly used in bone tissue engineering (BTE) due to their biocompatibility and adequate mechanical properties. However, their hydrophobicity and the lack of specific cell recognition sites confined their practical ...
Liang Dong   +4 more
semanticscholar   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Measurement of collagen synthesis by cells grown under different mechanical stimuli [PDF]

open access: yes, 2006
INTRODUCTION: The use of scaffolds in tissue engineering is essential to provide cells with a matrix for cell proliferation and differentiation resulting in tissue regeneration.
Brown, R, Foroughi, F, Mudera, V
core  

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