Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target
Jiewen Liao +10 more
wiley +1 more source
<i>In vitro</i> and <i>i</i> <i>n vivo</i> assessment of biomineralized amorphous silica fiber scaffolds for bone tissue engineering. [PDF]
Kim HS +4 more
europepmc +1 more source
Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi +2 more
wiley +1 more source
A Transport-Driven Conceptual Framework for the Biodegradation of FFF-Printed PLA/PHB Structures: Integrating Evidence from Complementary Experimental Studies. [PDF]
Balogová AF +4 more
europepmc +1 more source
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park +5 more
wiley +1 more source
Toward 4D Biomaterials: Comparing Electrospun and 3D-Printed Shape-Memory Scaffolds. [PDF]
Ruccolo L +9 more
europepmc +1 more source
A polymeric graft loaded with radiopaque bismuth nanoparticles is expected to undergo gradual polymer resorption and nanoparticle release. This design enables noninvasive, multimodal monitoring of device integrity, patency, and degradation using computed tomography alongside ultrasound and photoacoustic imaging over 12 weeks.
Allan John R. Barcena +13 more
wiley +1 more source
Influence of carboxymethyl cellulose and calcium-crosslinked CMC coating of 3D-Printed hydroxyapatite scaffolds on the early hemostatic performance and osteoblastic compatibility. [PDF]
Deedklin A +4 more
europepmc +1 more source
Azobenzene photoswitches translate molecular‐scale E/Z photoisomerization into macroscopic material responses and device‐level photonic functions. This Review highlights how azobenzene research has evolved from molecular photochemistry to photoalignment, mass migration, photomechanics, and heat release, ultimately enabling holography, reconfigurable ...
Heeju Son +20 more
wiley +1 more source
Chemical Scaffolds Driving Modern Anticancer Drug Discovery and Radiotheranostics: Structural Determinants, Translational Opportunities and Future Perspectives. [PDF]
Rusek M.
europepmc +1 more source

