Results 131 to 140 of about 429,461 (336)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Étayage en ligne et développement de la conscience métacognitive

ALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2019
The following article describes a case study based on a telecollaboration between two groups of learners studying French as a second/foreign language. Supported by Activity Theory and the notion of scaffolding, we seek to analyse whether collaborative ...
Catherine Caws, Eliane Lousada, Arthur Marra   +2 more
doaj   +1 more source

'Scaffolding': learning in the classroom

, 1992
Recent interest in talk and learning in the classroom has encouraged a new metaphorical use for the term 'scaffolding'. This term is increasingly used to describe certain kinds of support which learners receive in their interaction with parents, teachers
Maybin, Janet, Mercer, Neil, Stierer, Barry   +2 more
core  

Scaffolding, organisational structure and interpersonal interaction in musical activities with older people [PDF]

, 2013
The research reported here focuses on the organizational structure and facilitator strategies observed in musical activities with older people. The observations formed one part of the Music for Life Project, funded by the ESRC New Dynamics of Ageing ...
Creech, Andrea, Gaunt, Helena, Hallam, Sue, McQueen, Hilary, Varvarigou, Maria   +4 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Analysis of students' dual processes in solving number pattern questions and providing scaffolding

Journal Focus Action of Research Mathematic
This research aims to describe students' dual-process in solving number pattern questions and scaffolding that support students' dual-process. This research uses a qualitative research approach with a case study type.
Ganis Irma Firnanda, Susiswo
doaj   +1 more source

The legal and technical possibilities of using of scaffoldings as the ramp for disabled persons

Budownictwo i Architektura, 2015
The paper is devoted to the problems of legal and technical making the ramp for disabled persons with scaffolds. Scaffolding system components allow you to assemble a structure that serve as the ramp and fulfil the requirements of technical conditions ...
Ewa Błazik-Borowa, Michał Pieńko, Aleksander Robak   +2 more
doaj   +1 more source

Coordinates, observables and symmetry in relativity

, 2009
We investigate the interplay and connections between symmetry properties of equations, the interpretation of coordinates, the construction of observables, and the existence of physical relativity principles in spacetime theories. Using the refined notion
Anderson, Barbour, Bergmann, Bluman, Brown, Brown, Brown, Cantwell, DeWitt, Dittrich, Dittrich, Earman, Earman, Einstein, Einstein, Einstein, Einstein, Ferrario, Friedman, Giulini, Hans Westman, Hawking, Ibragimov, Ibragimov, Ibragimov, Ibragimov, Iftime, Kiefer, Kretschmann, Kuchar, Misner, Norton, Olver, Rovelli, Rovelli, Sebastiano Sonego, Sorkin, Stachel, Stachel, Varadarajan, Wald, Westman   +41 more
core   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Fremde Sprachen lernen durch die Lektüre öffentlicher Räume

Journal of Linguistics and Language Teaching, 2020
Öffentliche Räume bieten ein ideales Gerüst zur Unterstützung beim Erlernen fremder Sprachen (scaffolding), denn hier erscheinen kurze, oft standardisierte und in leichten Variationen häufig wiederholte Texte an Stellen, deren vorstrukturierter ...
Ulrich Schmitz
doaj