Results 71 to 80 of about 160,812 (310)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Scaffolding Strategy In Mathematics Learning

open access: yes, 2011
Mathematics learning should be designed so that it is oriented to the goal which is focused on process. Learning orientation is focused on the development of ‘mathematical thinking’ and ‘mathematical disposition’.
Tedy , Machmud
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Pedagogic scaffolding practices of primary mathematics teachers

open access: yes, 2009
Includes abstract.Includes bibliographical references (leaves 150-158).This study describes the pedagogical scaffolding practices of nine primary school teachers in 18 lessons in the foundation phase.
Schmitt, Esme
core  

Scaffolding. Spanish

open access: yes, 2021
Title from PDF caption (viewed on June 25, 2021)."OR-OSHA (6/21) FS-79-S"--Page 2."División 3, Subdivisión L."This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Scaffolding learners in authentic, problem based e-learning environments: The geography challenge

open access: yes, 2006
The affordances of online learning technologies have enabled more widespread development of learning environments that facilitate the exploration and solving of complex and realistic problems.
Brickell, G., Herrington, J.
core  

The nature of scaffolding interaction: mother and child contribution across time and culture [PDF]

open access: yes, 2018
Children’s learning within the home can be characterised by variety in the cognitive, behavioural and affective contributions of both mother and child, as well as by the wider environmental influences on family functioning. The concept of scaffolding may
Cooper, E.
core  

The Influence of Causal Thinking with Scaffolding Type 2A and 2B on Optics Problem-Solving Ability

open access: yesJurnal Pendidikan Fisika Indonesia, 2018
The effectiveness of learning is affected by the assistance stages (scaffolding) provided. For example, the scaffolding of type 2a and type 2b supports the causal-thinking approach in learning.
N. Nurmadiah, J. Rokhmat, S. Ayub
doaj   +1 more source

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