Results 111 to 120 of about 7,486,996 (336)

DeepMIP: model intercomparison of early Eocene climatic optimum (EECO) large-scale climate features and comparison with proxy data [PDF]

, 2021
Daniel J. Lunt, Fran Bragg, Wing‐Le Chan, David K. Hutchinson, Jean‐Baptiste Ladant, Polina Morozova, Igor Niezgodzki, Sebastian Steinig, Zhongshi Zhang, Jiang Zhu, Ayako Abe‐Ouchi, Eleni Anagnostou, Agatha M. de Boer, Helen K. Coxall, Yannick Donnadieu, Gavin L. Foster, Gordon N. Inglis, Gregor Knorr, Petra M. Langebroek, Caroline H. Lear, Gerrit Lohmann, Christopher J. Poulsen, Pierre Sepulchre, Jessica E. Tierney, Paul J. Valdes, E. M. Volodin, Tom Dunkley Jones, Christopher J. Hollis, Matthew Huber, Bette L. Otto‐Bliesner   +29 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Scalar: Systematic Scalability Analysis with the Universal Scalability Law

2014 International Conference on Future Internet of Things and Cloud, 2014
Analyzing the scalability and quality of service of large scale distributed systems requires a highly scalable benchmarking framework with built-in communication and synchronisation functionality, which are features that are lacking in current load generation tools. This paper documents Scalar, our distributed, extensible scalability analysis tool that
Heyman, Thomas, Preuveneers, Davy, Joosen, Wouter   +2 more
openaire   +2 more sources

Scalability-first pointer analysis with self-tuning context-sensitivity

ESEC/SIGSOFT FSE, 2018
Context-sensitivity is important in pointer analysis to ensure high precision, but existing techniques suffer from unpredictable scalability. Many variants of context-sensitivity exist, and it is difficult to choose one that leads to reasonable analysis ...
Yue Li, Tian Tan, Anders Møller, Y. Smaragdakis   +3 more
semanticscholar   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Introduction by Mark Stiles to Part 3 of Littlejohn, A. (2003) Reusing Online Resources: Resource Perspectives

Journal of Interactive Media in Education, 2004
: In Chapter 11, 'Digital libraries and repositories', Charles Duncan and Cuna Ekmekcioglu have kept the 'learning' emphasis [it's all about people and how they learn and not about just giving people resources'] but also recognize the many barriers and ...
Mark J. Stiles
doaj   +1 more source

Factors that Impact Blockchain Scalability

International ACM Conference on Management of Emergent Digital EcoSystems, 2019
Blockchain systems (more precisely Distributed Ledger Technologies (DLTs)) represent a different digital ecosystem compared with traditional computer systems.
Peter W. Eklund, R. Beck
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

PHIBSS: Unified Scaling Relations of Gas Depletion Time and Molecular Gas Fractions* [PDF]

, 2018
L. J. Tacconi, R. Genzel, A. Saintonge, F. Combes, S. Garcia-Burillo, R. Neri, A. Bolatto, T. Contini, N. M. Förster Schreiber, S Lilly, D. Lutz, S. Wuyts, G. Accurso, J. Boissier, F. Boone, N. Bouché, F. Bournaud, A. Burkert, M. Carollo, M Cooper, P COX, C Feruglio, J C Freundlich, R. Herrera-Camus, S. Juneau, M Lippa, T Naab, A. Renzini, P. Salomé, A. Sternberg, K. Tadaki, H. Übler, F. Walter, B. Weiner, A. Weiss   +34 more
openalex   +1 more source

Towards integrated care for older people: experiences from two local initiatives in Catalonia (within the SUSTAIN project)

International Journal of Integrated Care, 2019
Background: Two local initiatives (North Sabadell and Osona) within the SUSTAIN European research project have developed improvement projects aiming to better implement person-centred integrated care for older people living at home.
Lina Masana, Jillian Reynolds, Lidia Palau, Ivana Valdelvira, Olga Bigas, Pilar Fernández Morral, Joan Espaulella, Carme Guinovart, Sebastià Santaeugènia, Joan Carles Contel Segura, Nuri Cayuelas-Mateu, Mireia Espallargues   +11 more
doaj   +1 more source