Results 151 to 160 of about 1,696,641 (325)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

A review of site-controlled compound semiconductor quantum dots for single photon emitters

open access: yesMaterials for Quantum Technology
Single photon emitters (SPEs) serve as the fundamental building blocks of photonic networks for applications in quantum information science and technology.
Yaonan Hou
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

The Blockchain Trilemma: A Formal Proof of the Inherent Trade-Offs Among Decentralization, Security, and Scalability

open access: yesApplied Sciences
Blockchain technology has emerged as a transformative force with the potential to disrupt traditional industries by providing decentralized, secure, and transparent systems. However, blockchain systems face a fundamental challenge known as the Blockchain
Souhail Mssassi, Anas Abou El Kalam
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

A Quality of Service Driven Approach for Clustering in Mobile Ad hoc Networks Based on Metrics Adaptation: Looking Beyond Clustering

open access: yesJournal of Communications Software and Systems, 2008
Recently, research topics are focusing on clustering approaches for Ad hoc networks due to their effectiveness in building a virtual backbone formed by a set of suitableclusterheads (CH) to guarantee the communications acrossclusters.
Zouhair El-Bazzal   +4 more
doaj  

A scalability analysis of grid allocation mechanisms [PDF]

open access: yes
This article examines the broker's behavior with regard to a varying number of participating nodes and shows that incremental losses have to be accepted in central resource allocation when introducing new nodes.
Eymann, Torsten   +2 more
core  

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