Results 61 to 70 of about 38,230 (266)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Low-cost predefined-time convergent super-twisting algorithm
Franklin OpenThis paper presents a modified super-twisting control algorithm that drives the state of a scalar system at the origin for a predefined-time with a low control cost.
Ramon Lopez, Michael Basin
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Development of Quantitative and Temporal Scalar Implicatures in a Felicity Judgment Task
Frontiers in Psychology, 2019 Experimental investigations into children’s interpretation of scalar terms show that children have difficulties with scalar implicatures in tasks. In contrast with adults, they are for instance not able to derive the pragmatic interpretation that “some ...
Walter Schaeken +2 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
IEEE Access, 2019 This paper presents a discrete-time adaptive control approach for nonlinear systems with input delay. The nonlinearity is assumed to be non-sector bounded, resulting in the key technical lemma being inapplicable.
Khalid Abidi, Ian Postlethwaite
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Auxiliary Converter with Voltage Closed-loop Control
Kongzhi Yu Xinxi Jishu, 2012 According to the operation characteristics of auxiliary converter, based on voltage closed-loop and constant control strategy of the ratio between voltage and frequency square, it studied output voltage fluctuation of auxiliary converter and heavy load ...
TANG Zihui, JIANG Xuejun, WEI Gang
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Sensorless Predictive Multiscalar-Based Control of the Five-Phase IPMSM
IEEE AccessThis article proposes multi-scalar variables based predictive control of sensorless multiphase interior permanent magnet synchronous machine. Estimated parameters from adaptive observers are used to implement the proposed control scheme.
Deepak Vyas +4 more
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Generalised dissipative asynchronous output feedback control for Markov jump repeated scalar non‐linear systems with time‐varying delay [PDF]
, 2019 Jing Wang +5 more
openalex +1 more source