Results 161 to 170 of about 193,587 (326)

Non-degeneracy of multi-bubbling solutions for prescribed scalar curvature problem via local Pohozaev identity [PDF]

, 2022
Qingfang Wang
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Singular metrics with negative scalar curvature [PDF]

, 2021
Man-Chuen Cheng, Man-Chun Lee, Luen-Fai Tam   +2 more
openalex   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Appearance of stable minimal spheres along the Ricci flow in positive scalar curvature [PDF]

, 2019
Antoine Song
openalex   +1 more source

Singular scalar curvature equations

, 2022
We develop estimates for the equation of scalar curvature of singular metrics with cone angle $\beta>1$, in a big and semi-positive cohomology class on a K\"ahler manifold. We further derive the Laplacian estimate for the scalar curvature equation of degenerate K\"ahler metrics.
openaire   +1 more source

Prescribing Scalar Curvatures: Loss of Minimizability

The Journal of Geometric Analysis
Prescribing conformally the scalar curvature on a closed manifold with negative Yamabe invariant as a given function $K$ is possible under smallness assumptions on $K_{+}=\max\{K,0\}$ and in particular, when $K<0$. In addition, while solutions are unique in case $K\leq 0$, non uniqueness generally holds, when $K$ is sign changing and $K_ ...
Martin Mayer, Chaona Zhu
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

SCALAR CURVATURE OF HYPERSURFACES WITH CONSTANT MEAN CURVATURE IN SPHERES [PDF]

, 2011
Qin Zhang
openalex   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source