Results 151 to 160 of about 193,587 (326)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

On Curvature Pinching for Submanifolds with Parallel Normalized Mean Curvature Vector

open access: yesMathematics
In this note, we investigate the pinching problem for oriented compact submanifolds of dimension n with parallel normalized mean curvature vector in a space form Fn+p(c).
Juanru Gu, Yao Lu
doaj   +1 more source

Prescribing scalar curvature on \( S^{3} \)

open access: yesAnnales de l'Institut Henri Poincaré C, Analyse non linéaire, 2007
We give existence results for solutions of the prescribed scalar curvature equation on S^{3} , when the curvature function is a positive Morse function and satisfies an index-count condition.
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Infinite loop spaces and positive scalar curvature [PDF]

open access: green, 2017
Boris Botvinnik   +2 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Einstein like -para Sasakian manifolds

open access: yesKuwait Journal of Science, 2013
Einstein like  -para Sasakian manifolds are introduced. For an  -para Sasakian manifold to be Einstein like, a necessary and sufficient condition in terms of its curvature tensor is obtained.
SADIK KELES   +3 more
doaj  

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