Results 141 to 150 of about 13,851 (306)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Multiply Warped Products with a Semisymmetric Metric Connection
Abstract and Applied Analysis, 2014 We study the Einstein multiply warped products with a semisymmetric metric connection and the multiply warped products with a semisymmetric metric connection with constant scalar curvature, and we apply our results to generalized Robertson-Walker space ...
Yong Wang
doaj +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Mathematische Zeitschrift, 1989 The author shows the following result: If \(m\not\equiv 1\) (Mod 4), and \(m\geq 4\), every smooth function of \(S^ m\) is the scalar curvature of some metric of unit total volume.
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Scalar Curvature in Dimension 4
We prove that every locally conformally flat metric on a closed, oriented hyperbolic $4$-manifold with scalar curvature bounded below by $-12$ satisfies Schoen’s conjecture.
Deng, Jialong
core +1 more source
On Curvature Pinching for Submanifolds with Parallel Normalized Mean Curvature Vector
MathematicsIn this note, we investigate the pinching problem for oriented compact submanifolds of dimension n with parallel normalized mean curvature vector in a space form Fn+p(c).
Juanru Gu, Yao Lu
doaj +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
On scalar curvature in lightlike geometry
Journal of Geometry and Physics, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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