Results 171 to 180 of about 681,612 (344)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster+3 more
wiley +1 more source
On Curvature Pinching for Submanifolds with Parallel Normalized Mean Curvature Vector
In this note, we investigate the pinching problem for oriented compact submanifolds of dimension n with parallel normalized mean curvature vector in a space form Fn+p(c).
Juanru Gu, Yao Lu
doaj +1 more source
Scalar concomitants of a metric and a curvature form. II [PDF]
R. J. Noriega, C. G. Schifini
openalex +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng+13 more
wiley +1 more source
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian+10 more
wiley +1 more source
Prescribing Scalar Curvatures on the Conformal Classes of Complete Metrics with Negative Curvature [PDF]
Zhiren Jin
openalex +1 more source
Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang+6 more
wiley +1 more source
Einstein like -para Sasakian manifolds
Einstein like -para Sasakian manifolds are introduced. For an -para Sasakian manifold to be Einstein like, a necessary and sufficient condition in terms of its curvature tensor is obtained.
SADIK KELES+3 more
doaj
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash+6 more
wiley +1 more source
Super-energy tensor for space–times with vanishing scalar curvature [PDF]
Miguel Á. G. Bonilla+1 more
openalex +1 more source