Results 171 to 180 of about 292,024 (345)
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into âcold tumorsâ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
Scalar concomitants of a metric and a curvature form. II [PDF]
R. J. Noriega, C. G. Schifini
openalex +1 more source
On scalar curvature rigidity of Vacuum Static Spaces [PDF]
In this paper we extend the local scalar curvature rigidity result in [6] to a small domain on general vacuum static spaces, which confirms the interesting dichotomy of local surjectivity and local rigidity about the scalar curvature in general in the light of the paper [10].
arxiv
A potential tumor suppressor role of PLK2 in glioblastoma
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia+5 more
wiley +1 more source
An integral formula on the scalar curvature of algebraic manifolds [PDF]
Jih Hsin ChĂȘng
openalex +1 more source
Identification of inhibitors of the Salmonella FraB deglycase, a drug target
A highâthroughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixedâtype inhibitors of FraB.
Jamison D. Law+6 more
wiley +1 more source
Einstein like -para Sasakian manifolds
Einstein like -para Sasakian manifolds are introduced. For an -para Sasakian manifold to be Einstein like, a necessary and sufficient condition in terms of its curvature tensor is obtained.
SADIK KELES+3 more
doaj
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)âinduced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGOâinduced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang+7 more
wiley +1 more source
Prescribing Scalar Curvatures on the Conformal Classes of Complete Metrics with Negative Curvature [PDF]
Zhiren Jin
openalex +1 more source