Results 71 to 80 of about 45,707 (265)
Extending Scatterplots to Scalar Fields
Embedding high-dimensional data into a 2D canvas is a popular strategy for their visualization.
Shenghui Cheng +2 more
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Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
This paper is devoted to presenting the dynamics of thin-shell composed of massive and massless scalar fields developed from (2+1)-dimensional rotating black holes with nonminimally coupled scalar fields.
Faisal Javed +6 more
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
We show that a canonical, minimally coupled scalar field which is non-self interacting and massless is equivalent to a null dust fluid (whether it is a test or a gravitating field), in a spacetime region in which its gradient is null.
Valerio Faraoni, Jeremy Côté
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
FIELD REDEFINITION AND RENORMALIZABILITY IN SCALAR FIELD THEORIES
We have addressed the issue of field redefinition in connection with renormalizability. Our study is restricted to theories of interacting scalar fields. We have, in particular, shown that if a theory is renormalizable in the usual power-counting sense then it remains renormalizable in the same sense after a change of variables. This is due to the use
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Spontaneous scalarization with massive fields
We study the effect of a mass term in the spontaneous scalarization of neutron stars, for a wide range of scalar field parameters and neutron star equations of state. Even though massless scalars have been the focus of interest in spontaneous scalarization so far, recent observations of binary systems rule out most of their interesting parameter space.
Ramazanoğlu, Fethi M, Pretorius, Frans
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