Results 81 to 90 of about 669,527 (312)
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
Scalar field dark matter with spontaneous symmetry breaking and the 3.5 keV line
Physics Letters B, 2018 We show that the present dark matter abundance can be accounted for by an oscillating scalar field that acquires both mass and a non-zero expectation value from interactions with the Higgs field.
Catarina Cosme +2 more
doaj
Some cosmological consequences of higher dimensional Klein–Gordon–Rastall theory
European Physical Journal C: Particles and Fields, 2023 Using dynamical system analysis, we investigate some cosmological consequences of Rastall gravity coupled to a scalar field (called the Klein–Gordon–Rastall theory) with exponential scalar potential turned on in higher dimensions.
Tegar Ari Widianto +4 more
doaj +1 more source
Cosmological scalar fields and Big-Bang nucleosynthesis [PDF]
arXiv, 2020 The nature of dark matter and of dark energy which constitute more than $95\%$ of the energy in the Universe remains a great and unresolved question in cosmology. Cold dark matter can be made of an ultralight scalar field dominated by its mass term which interacts only gravitationally.
arxiv
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Molecular Oncology, EarlyView.Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson +11 more
wiley +1 more source
Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
Dark fluid: A complex scalar field to unify dark energy and dark matter [PDF]
Physical Review D, 2006 9 pages, 3 figures, references added, minor corrections and ...
Alexandre Arbey, Alexandre Arbey
openaire +3 more sources
A potential tumor suppressor role of PLK2 in glioblastoma
FEBS Open Bio, EarlyView.PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia +5 more
wiley +1 more source
Thermal Misalignment of Scalar Dark Matter [PDF]
arXiv, 2021 The conventional misalignment mechanism for scalar dark matter depends on the initial field value, which governs the oscillation amplitude and present-day abundance. We present a mechanism by which a feeble (Planck-suppressed) coupling of dark matter to a fermion in thermal equilibrium drives the scalar towards its high-temperature potential minimum at
arxiv
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, EarlyView.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source