Results 81 to 90 of about 106,793 (315)

Model for a Universe described by a non-minimally coupled scalar field and interacting dark matter

, 2006
In this work it is investigated the evolution of a Universe where a scalar field, non-minimally coupled to space-time curvature, plays the role of quintessence and drives the Universe to a present accelerated expansion.
A.G. Riess, A.G. Riess, A.R. Liddle, C. Wetterich, D.S.M. Alves, G. Esposito-Farèse, G. M. Kremer, G.R. Farrar, I. Prigogine, J. B. Binder, J.A. Casas, J.P. Uzan, J.S. Alcaniz, L. Amendola, L. Amendola, L.R. Abramo, M. Fukugita, M. Persic, M.S. Madsen, S. Perlmutter, S.D.H. Hsu, S.M. Carroll, S.M. Carroll, T. Chiba, V. Faraoni   +24 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Some cosmological consequences of higher dimensional Klein–Gordon–Rastall theory

European Physical Journal C: Particles and Fields, 2023
Using dynamical system analysis, we investigate some cosmological consequences of Rastall gravity coupled to a scalar field (called the Klein–Gordon–Rastall theory) with exponential scalar potential turned on in higher dimensions.
Tegar Ari Widianto, Ahmad Khoirul Falah, Agus Suroso, Husin Alatas, Bobby Eka Gunara   +4 more
doaj   +1 more source

A two measure model of dark energy and dark matter

, 2012
In this work we construct a unified model of dark energy and dark matter. This is done with the following three elements: a gravitating scalar field, phi with a non-conventional kinetic term, as in the string theory tachyon; an arbitrary potential, V(phi)
Douglas Singleton, E. Bergshoeff, E. Guendelman, E. Guendelman, E.A. Lim, Eduardo Guendelman, N Yongram, S. Ansoldi, S. del Campo, Supernova Cosmology Project collaboration, Supernova Search Team collaboration, U. Alam, V. Sahni   +12 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Spontaneous electro-weak symmetry breaking and cold dark matter

, 2006
In the standard model, the weak gauge bosons and fermions obtain mass after spontaneous electro-weak symmetry breaking, which is realized through one fundamental scalar field, namely Higgs field.
Bergstrom L, de Boer W, de Boer W, Djouadi A, Juste A, Kolb E W, Zhu Shou-Hua   +6 more
core   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Interacting Dark Matter and Dark Energy

, 2003
We discuss models for the cosmological dark sector in which the energy density of a scalar field approximates Einstein's cosmological constant and the scalar field value determines the dark matter particle mass by a Yukawa coupling. A model with one dark
Damour T., Dirac P. A. M., Fierz M., Glennys R. Farrar, Nordstrom G., P. J. E. Peebles, Wetterich C.   +6 more
core   +1 more source

Dark fluid: A complex scalar field to unify dark energy and dark matter [PDF]

Physical Review D, 2006
9 pages, 3 figures, references added, minor corrections and ...
Alexandre Arbey, Alexandre Arbey
openaire   +3 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source