Results 41 to 50 of about 100,158 (234)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The Sums and Products of Commuting AC-Operators
International Journal of Industrial Engineering and Production Research, 2007 : In this paper, we exhibit new conditions for the sum of two commuting AC-operators to be again an AC-operator. In particular, this is satisfied on Hilbert space when one of them is a scalar-type spectral operator.
M.B Ghaemi, p. Spain
doaj
European Physical Journal C: Particles and FieldsThe spectral curve of quasinormal modes for a massive real scalar field in the background of a non-conformal black brane geometry has been obtained by utilizing a Frobenius type near-horizon expansion.
Ashis Saha, Sunandan Gangopadhyay
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Basso-Dixon Correlators in Two-Dimensional Fishnet CFT
, 2019 We compute explicitly the two-dimensional version of Basso-Dixon type integrals for the planar four-point correlation functions given by conformal fishnet Feynman graphs.
Derkachov, Sergey +2 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
The Egorov theorem for transverse Dirac type operators on foliated manifolds
, 2007 Egorov's theorem for transversally elliptic operators, acting on sections of a vector bundle over a compact foliated manifold, is proved. This theorem relates the quantum evolution of transverse pseudodifferential operators determined by a first order ...
Bolte +27 more
core +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
On Noncommutative and semi-Riemannian Geometry
, 2002 We introduce the notion of a semi-Riemannian spectral triple which generalizes the notion of spectral triple and allows for a treatment of semi-Riemannian manifolds within a noncommutative setting.
Alexander Strohmaier +16 more
core +3 more sources