Results 131 to 140 of about 1,692,270 (273)

Nonlocal evolution of weighted scale-free networks

, 2006
We introduce the notion of globally updating evolution for a class of weighted networks, in which the weight of a link is characterized by the amount of data packet transport flowing through it.
B. Kahng, D. Kim, E. V. Koonin, K.-I. Goh, P. Holme, R. Pastor-Satorras, S. N. Dorogovtsev   +6 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Explosive Percolation in Scale-Free Networks

Physical Review Letters, 2009
We study scale-free networks constructed via a cooperative Achlioptas growth process. Links between nodes are introduced in the network in order to produce a scale-free graph with given exponent lambda for the degree distribution, but the choice of each new link depends on the mass of the clusters that this link will merge.
Radicchi, Filippo, Fortunato, Santo
openaire   +3 more sources

Scale free networks of earthquakes and aftershocks

, 2003
We propose a new metric to quantify the correlation between any two earthquakes. The metric consists of a product involving the time interval and spatial distance between two events, as well as the magnitude of the first one.
A. Helmstetter, A. Wagner, B. Gutenberg, C. Frohlich, C. H. Scholz, D. P. Hill, D. Stauffer, D. Turcotte, F. Omori, G. M. Molchan, J. Gardner, L. Knopoff, L. Knopoff, M. Faloutsos, Marco Baiesi, Maya Paczuski, P. Bak, P. Bak, T. Hirata, T. Utsu, V. Keilis-Borok, Y. Y. Kagan   +21 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Penalized homophily latent space models for directed scale-free networks. [PDF]

PLoS One, 2021
Yang H, Xiong W, Zhang X, Wang K, Tian M.   +4 more
europepmc   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

True scale-free networks hidden by finite size effects. [PDF]

Proc Natl Acad Sci U S A, 2021
Serafino M, Cimini G, Maritan A, Rinaldo A, Suweis S, Banavar JR, Caldarelli G.   +6 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source