Results 81 to 90 of about 758,831 (346)

RSAP-Net: joint optic disc and cup segmentation with a residual spatial attention path module and MSRCR-PT pre-processing algorithm

open access: yesBMC Bioinformatics, 2022
Background Glaucoma can cause irreversible blindness to people’s eyesight. Since there are no symptoms in its early stage, it is particularly important to accurately segment the optic disc (OD) and optic cup (OC) from fundus medical images for the ...
Yun Jiang   +4 more
doaj   +1 more source

Is segmentation uncertainty useful? [PDF]

open access: yesarXiv, 2021
Probabilistic image segmentation encodes varying prediction confidence and inherent ambiguity in the segmentation problem. While different probabilistic segmentation models are designed to capture different aspects of segmentation uncertainty and ambiguity, these modelling differences are rarely discussed in the context of applications of uncertainty ...
arxiv  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas   +15 more
wiley   +1 more source

iMSCGnet: Iterative Multi-Scale Context-Guided Segmentation of Skin Lesion in Dermoscopic Images

open access: yesIEEE Access, 2020
Despite much effort has been devoted to skin lesion segmentation, the performance of existing methods is still not satisfactory enough for practical applications. The challenges may include fuzzy lesion boundary, uneven and low contrast, and variation of
Yujiao Tang   +6 more
semanticscholar   +1 more source

Objective-Dependent Uncertainty Driven Retinal Vessel Segmentation [PDF]

open access: yesarXiv, 2021
From diagnosing neovascular diseases to detecting white matter lesions, accurate tiny vessel segmentation in fundus images is critical. Promising results for accurate vessel segmentation have been known. However, their effectiveness in segmenting tiny vessels is still limited.
arxiv  

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

SBNet: Sparse Blocks Network for Fast Inference

open access: yes, 2018
Conventional deep convolutional neural networks (CNNs) apply convolution operators uniformly in space across all feature maps for hundreds of layers - this incurs a high computational cost for real-time applications.
Pokrovsky, Andrei   +3 more
core   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Research on Fault Diagnosis of Rolling Bearing Based on Morlet Wavelet and Scale Space

open access: yes机车电传动, 2021
Aiming at the difficulty of extracting the early fault features of rolling bearings, a rolling bearing fault diagnosis method based on Morlet wavelet and scale space was proposed.
Maohui WANG   +3 more
doaj  

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

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