Results 131 to 140 of about 1,957,056 (283)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Romanian Version of the Oral Health Values Scale: Adaptation and Validation. [PDF]

Medicina (Kaunas), 2022
Balgiu BA, Sfeatcu R, Mihai C, Lupușoru M, Bucur MV, Tribus L.   +5 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Validity and Reliability of the Turkish Version of the Short-Form Safety Climate Scale for Healthcare Institutions: A Methodological Study

İşletme Bilimi Dergisi
The Safety Climate Scale is an essential tool for understanding employees’ shared perceptions of occupational safety but required adaptation for use in Turkish healthcare settings.
Musa Özata, Lale Karasu, Emre Karasu
doaj   +1 more source

Flourishing Scale: Adaptation and Evidence of Validity in a Chilean High School Context. [PDF]

Front Psychol, 2022
Carmona-Halty M, Marín-Gutierrez M, Mena-Chamorro P, Sepulveda-Páez G, Ferrer-Urbina R.   +4 more
europepmc   +1 more source

Scale-Adaptive Superpixels [PDF]

Color and Imaging Conference, 2018
Radhakrishna Achanta, Pablo Márquez-Neila, Pascal Fua, Sabine Süsstrunk   +3 more
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Measurement invairance and construct validity of the Turkish version of the learner autonomy scale in a sample of high and secondary school students

International Journal of Contemporary Educational Research
The goal of this research is to adapt the 24-item "Learner Autonomy Scale" developed by Sereti and Giossos (2018) in higher education samples into Turkish by examining the psychometric properties of high school and secondary school samples, and to ...
Emrullah Deniz, Hilal Kazu
doaj   +1 more source

The Quality of Carer-Patient Relationship Scale: Adaptation and Validation into Portuguese. [PDF]

Int J Environ Res Public Health, 2021
Silva R, Bobrowicz-Campos E, Santos-Costa P, Gil I, Neves H, Apóstolo J.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source