Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The internet can make everyday life more accessible; however, it can also cause problematic behavior. It is essential to prevent the negative impact of problematic internet use on daily activities, whether in educational settings, work, social life, or ...
Dhia Ulfah Purwati, Hanifah Hanifah
doaj +1 more source
Stigma Scale Adaptation and Validation for Measuring COVID-19 Stigma. [PDF]
Pallavi P +4 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Validation of Hospital Anxiety and Depression Scale in an Indonesian population: a scale adaptation study. [PDF]
Tiksnadi BB +5 more
europepmc +1 more source
Detecting Adaptation with Genome-Scale Molecular Evolutionary Analysis: An Educational Primer for Use with “RNA Interference Pathways Display High Rates of Adaptive Protein Evolution in Multiple Invertebrates” [PDF]
Brian P. Lazzaro
openalex +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Portuguese version of Bern Illegitimates Task Scale: adaptation and evidence of validity. [PDF]
Neves PC +3 more
europepmc +1 more source
TURKISH ADAPTATION OF THE PERCEIVED STIGMA SCALE AFTER COVID-19
Gülşen Karaman +99 more
openalex +1 more source
Italian adaptation of the Düsseldorf Orthorexia Scale (I-DOS): psychometric properties and prevalence of orthorexia nervosa among an Italian sample [PDF]
Silvia Cerolini +5 more
openalex +1 more source

