Results 141 to 150 of about 10,065,631 (384)

Adaptive Computing for Scale-Up Problems

open access: yesComputing in Science & Engineering
Adaptive Computing is an application-agnostic outer loop framework to strategically deploy simulations and experiments to guide decision making for scale-up analysis. Resources are allocated over successive batches, which makes the allocation adaptive to some objective such as optimization or model training.
Kevin Patrick Griffin   +13 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Turkish Validity and Reliability Study of (Trait) Empathic Anger Scale

open access: yesYaşam Becerileri Psikoloji Dergisi, 2019
The present study aims to adapt (Trait) Empathic Anger Scale (Vitaglione & Barlett, 2003) into Turkish and examine its psychometric properties. Empathic anger is defined as a feeling that is felt for the victim in the event of an injustice.
Nur Okutan
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Application of Scale-adaptive Dust Emission Scheme to CMA-CUACE/Dust

open access: yes应用气象学报
Sand and dust storms are significant natural disasters which affect East Asia and China in spring, occurring from March to May. Performances of CMA-CUACE/Dust, an operational Asian sand and dust storm numerical forecasting system of CMA since 2006, are ...
Zhou Chunhong   +8 more
doaj   +1 more source

Micro-level practices to adapt to climate change for African small-scale farmers: [PDF]

open access: yes
This paper discusses micro-level practices for adapting to climate change that are available to small-scale farmers in Africa. The analysis is based on a review of 17 studies about practices that boost small-scale farmers' resilience or reduce their ...
Artner, Astrid   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Fully Convolutional Tri-branch Network (FCTN) for Domain Adaptation

open access: yes, 2018
A domain adaptation method for urban scene segmentation is proposed in this work. We develop a fully convolutional tri-branch network, where two branches assign pseudo labels to images in the unlabeled target domain while the third branch is trained with
Kuo, C. -C. Jay   +2 more
core   +1 more source

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