Results 61 to 70 of about 1,091,788 (268)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Evaluation of technical efficiency of county referral hospitals in kenya and its determinants

open access: yesInternational Journal of Advanced Medical and Health Research, 2019
Background: Kenya's gross national income per capita of $ 2250 is significantly lower than the global average of $ 6977. In addition, Kenya Government's health expenditure as a percent of the total government budget is approximately 7% which falls below ...
Gilbert Koome Rithaa   +3 more
doaj   +1 more source

Efficient evaluation of scaled proximal operators

open access: yesCoRR, 2016
Quadratic-support functions [Aravkin, Burke, and Pillonetto; J. Mach. Learn. Res. 14(1), 2013] constitute a parametric family of convex functions that includes a range of useful regularization terms found in applications of convex optimization. We show how an interior method can be used to efficiently compute the proximal operator of a quadratic ...
Michael P. Friedlander, Gabriel Goh
openaire   +3 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Scale Efficient Training for Large Datasets

open access: yes2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
The rapid growth of dataset scales has been a key driver in advancing deep learning research. However, as dataset scale increases, the training process becomes increasingly inefficient due to the presence of low-value samples, including excessive redundant samples, overly challenging samples, and inefficient easy samples that contribute little to model
Qing Zhou, Junyu Gao 0001, Qi Wang 0009
openaire   +2 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

The Impact of Nonrenewable Resource Abundance on Factor Shares

open access: yesبرنامه‌ریزی و بودجه, 2019
The share of factors of production in the GDP of a country represents an overall picture of its aggregate production technology. The share of reproducible factors (i.e., physical capital and human capital), and the share of non-reproducible factors (i.e.,
Ali Motavasseli, Najmeh Khani-Saryazdi
doaj  

Data Envelopment Analysis (DEA) to Estimate Technical and Scale Efficiencies of Smallholder Pineapple Farmers in Ghana

open access: yesAgriculture
This study focuses on evaluating the technical and scale efficiencies of smallholder pineapple farmers in Ghana’s Central Region. We surveyed 320 participants selected using random sampling and applied an input-oriented Data Envelopment Analysis (DEA ...
Kwaku Boakye   +4 more
doaj   +1 more source

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