Results 41 to 50 of about 3,865,865 (314)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
With urbanization acceleration, ensuring urban water use security and sustainable water resource management has become a major global challenge. As a populous country, China faces increasingly severe challenges.
Tingyu Tao, Hao Zhang, Zikun Hu
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Technical efficiency of water use and its determinants, study at smallscale irrigation schemes in North-West Province, South Africa [PDF]
This paper analyses the efficiency with which water is used in small-scale irrigation schemes in North-West Province in South Africa and studies its determinants.
Buysse, Jeroen +3 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Data Envelopment Analysis (Dea) approach In efficiency transport manufacturing industry in Malaysia [PDF]
The objective of this study was to measure of technical efficiency, transport manufacturing industry in Malaysia score using the data envelopment analysis (DEA) from 2005 to 2010.
Abdul Talib, Basri, Abdullah, Mohd Fahmy
core
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
We used a data envelopment analysis (DEA) to examine the efficiency and performance of transport systems of landlocked African countries (LLACs).
Enagnon H. Fanou, Xuping Wang
doaj +1 more source
The unlikely Carnot efficiency
The efficiency of an heat engine is traditionally defined as the ratio of its average output work over its average input heat. Its highest possible value was discovered by Carnot in 1824 and is a cornerstone concept in thermodynamics.
Broeck, Christian Van den +3 more
core +1 more source

