Results 111 to 120 of about 2,021,170 (319)
Evaluation Scale of Sepsis II severity score
Сучасні медичні технології, 2019 Background. Actually sepsis is one of the main causes of high lethality among surgical patients. The purpose of this study. Is improvement of Sepsis severity evaluation Score based on available clinical and laboratory indicators.
V. A. Syplyviy +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Design plan : evaluation of IDRC's strategy to scale research results
, 2020 This evaluation report proposes an assessment methodology that focuses on how, and how well, the IDRC implemented its 2015 strategic objective ‘to invest in knowledge and innovation for large-scale positive change.’ It will identify lessons and ...
Ball, Louise +2 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2019 The ‘Governance and Accountability through Digitalization’ project was implemented from February 2017 until March 2019 in the rural areas of Arusha, Mtwara, Kigoma and Geita in Tanzania, and in the Nduta refugee camp in Kigoma. The
Pretari, Alexia
core +1 more source
Education as an enabler, not a requirement: ensuring access to self-care options for all
Sexual and Reproductive Health Matters, 2022 Caitlin Corneliess +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
A Critical-Historical Review of Program Evaluation and the Emerging Motif ‘Evaluation Science’
, 2020 Background: It is important to distinguish between evaluation as an inherent, automatic, affective process and Program Evaluation (Evaluation, with capitalised ‘E’) as an institution, and equally important to consider what a good understanding of ...
Fear, William James, William James Fear
core +1 more source
Neuropsychiatric Disease and Treatment, 2012 Hugo Cogo-Moreira,1 George B Ploubidis,2 Clara Regina Brandão de Ávila,3 Jair de Jesus Mari,1 Angela Maria Vieira Pinheiro41Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil ...
Cogo-Moreira H +4 more
doaj
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source