Results 11 to 20 of about 719,803 (305)

Scale-up and optimization of the synthesis of dual CBP/BRD4 inhibitor ISOX-DUAL [PDF]

open access: yes, 2022
ISOX-DUAL is a dual inhibitor of CBP/p300 (IC50 = 0.65 μM) and BRD4 (IC50 = 1.5 μM) bromodomains, and a useful chemical probe for epigenetic research.
Maple, Hannah J.   +19 more
core   +3 more sources

Synthesis and Scale Inhibition Performance of Serine - Modified Polyepoxysuccinic Acid Scale Inhibitor [PDF]

open access: yesCailiao Baohu, 2022
Polyepoxysuccinic acid (PESA) is a green and environmental scale inhibitor. Its application is limited due to its single functional group. In order to enhance its performance, an experiment was carried out by using serine (Ser) as the modifier to modify ...
LIU Xin - hua, GUAN Jun - xia, WANG Li - hong, FU Zhan - da, GAO Yu - hua, WEI Jin - fang, WANG Lei, YANG Yong, LI Wen - tao
doaj   +1 more source

Process Development and Scale-Up of the SOS1 Inhibitor MRTX0902 [PDF]

open access: yes, 2023
MRTX0902, a novel SOS1 inhibitor, is currently being evaluated in phase I trials for the treatment of cancer. The complexity of the molecule containing a pyrido[3,4-d]pyridazine core and a chiral amine moiety makes it a challenging target to prepare on ...
Thomas, Scattolin   +2 more
core   +1 more source

Research Progress on Scale Inhibition Properties and Mechanism of Scale Inhibitors [PDF]

open access: yesCailiao Baohu, 2021
Application of scale inhibitor is one of the most efficient and practical methods to solve the scale problem in industrial water treatment system. In this paper, the scale inhibition performance of different types of scale inhibitors was compared and ...
LIU Xin-hua, ZHANG Huai-fang, LIU Yue, SHU Shi-li, ZHANG Jin-ting, WEI Jin-fang, WANG Lei
doaj   +1 more source

Evaluation of microbial agents as corrosion and scale inhibitor for industrial cooling water applications

open access: yesWater Science and Technology, 2022
In this study, six strains of microbial agents were investigated as environmently friendly scale and corrosion inhibitors for industrial cooling water applications.
Yanglin Hu, Chuanmin Chen, Songtao Liu
doaj   +1 more source

Performance of N,O-Carboxymethyl Chitosan as Corrosion and Scale Inhibitors in CO2 Saturated Brine Solution

open access: yesIndonesian Journal of Chemistry, 2021
The presence of salts and dissolved gas like CO2 that is carried with natural gas and crude oil along the pipeline is the main reason for corrosion and scale formation.
Muhamad Jalil Baari   +2 more
doaj   +1 more source

The oligosuccinimide and modified polysuccinimide as green corrosion and scale inhibitors

open access: yesChimica Techno Acta, 2023
Corrosion and scale formation are crucial issues in the petroleum industry. They can inflict metal or other materials breakdown, leading to environmental pollution.
Muhamad Jalil Baari
doaj   +1 more source

High Return Performance of Calcium Phosphonate (Ca-DTPMP) Colloidal Inhibitors for Squeeze Treatment in Shale Formations

open access: yesFrontiers in Materials, 2020
The objective of this work was to develop nanomaterial inhibitor with long squeeze life for oil and gas production. Different surfactants, such as trisodium citrate (Na3Cit), cetyltrimethyl ammonium bromide, benzethonium chloride (Hyamine), and ...
Shujun Gao   +10 more
doaj   +1 more source

Study on pretreatment process of scale inhibition to reverse osmosis membrane

open access: yesMeitan kexue jishu, 2023
Reverse osmosis (RO) process is the most widely used method in the treatment of high mineralized mine water, but membrane fouling has been restricting the further development of RO process.
Rulin ZHOU, Zong LIU, Zhongmei ZHAO
doaj   +1 more source

The study of a highly efficient and environment-friendly scale inhibitor for calcium carbonate scale in oil fields

open access: yesPetroleum, 2021
A highly efficient and environment-friendly scale inhibitor (MA-VA-VS) was synthesized via free radical solution polymerization method, where maleic anhydride (MA), vinyl acetate (VA) and vinyl sulfonate (VS) acted as monomers, while ammonium persulfate ...
Heng Wang   +5 more
doaj   +1 more source

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