Results 71 to 80 of about 807,423 (305)

Finite mixture modeling using shape mixtures of the skew scale mixtures of normal distributions

open access: yesCommunications in Statistics - Simulation and Computation, 2019
This paper introduces the shape mixtures of the skew scale mixtures of normal distribution which are contained additional shape parameters to regulate skewness and kurtosis. We present a finite mixture model for this new family of distributions, which is a novel model-based tool for clustering heterogeneous data in the presence of skewed and heavy ...
Mostafa Tamandi, Ahad Jamalizadeh
openaire   +1 more source

Evaluation of in-cylinder mixture homogeneity in a diesel HCCI engine – A CFD analysis

open access: yesEngineering Science and Technology, an International Journal, 2016
Performance and emission characteristics of HCCI engines depend on achieving a good in-cylinder homogeneous mixture. The formation of in-cylinder mixture depends on many engine parameters, which need optimization.
N. Ramesh, J.M. Mallikarjuna
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Study of the material property of fish scale collagen by composing with other collagens

open access: yes四川大学学报. 自然科学版, 2016
In the present study, porcine and bovine collagen were mixed respectively with the matrix composed of fish scale type I collagen, and then the properties of the reconstructed collagen sponge were tested. The fourier transform infrared spectroscopy (FTIR)
DU Tian-Ming   +3 more
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reparameterized Scale Mixture of Rayleigh Distribution Regression Models with Varying Precision

open access: yesMathematics
In this paper, we introduce a new parameterization for the scale mixture of the Rayleigh distribution, which uses a mean linear regression model indexed by mean and precision parameters to model asymmetric positive real data. To test the goodness of fit,
Pilar A. Rivera   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Breakdown points for maximum likelihood estimators of location-scale mixtures

open access: yes, 2004
ML-estimation based on mixtures of Normal distributions is a widely used tool for cluster analysis. However, a single outlier can make the parameter estimation of at least one of the mixture components break down. Among others, the estimation of mixtures
Hennig, C
core  

Scaling Laws for Optimal Data Mixtures

open access: yesCoRR
Large foundation models are typically trained on data from multiple domains, with the data mixture--the proportion of each domain used--playing a critical role in model performance. The standard approach to selecting this mixture relies on trial and error, which becomes impractical for large-scale pretraining.
Mustafa Shukor   +6 more
openaire   +2 more sources

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