Results 61 to 70 of about 5,426,024 (302)

A First Look at the Performance of Nano-Grooved Heat Pipes

open access: yes, 2018
Passive thermal spreaders utilizing liquid/vapor phase-change mechanism such as heat pipes, have been widely used in the macro-scale thermal management of electronic devices for many years. Micro-fabrication techniques enabled the fabrication micro-scale
Akkus, Yigit   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An improved gray-scale transformation method for pseudo-color image enhancement [PDF]

open access: yesКомпьютерная оптика, 2019
Image enhancement is a very important process of image preprocessing and it plays a critical role in the improvement of image quality and the follow-up image analysis, which makes the research of image enhancement algorithm a hot research field.
Haibo Gao, Wenjuan Zeng, Jifeng Chen
doaj   +1 more source

Rayleigh-Benard Convection in Large-Aspect-Ratio Domains

open access: yes, 2004
The coarsening and wavenumber selection of striped states growing from random initial conditions are studied in a non-relaxational, spatially extended, and far-from-equilibrium system by performing large-scale numerical simulations of Rayleigh-B\'{e}nard
I. Catton   +5 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Neutrophil-to-Lymphocyte and Monocyte-to-Lymphocyte Ratios Are Independently Associated With the Severity of Autoimmune Encephalitis

open access: yesFrontiers in Immunology, 2022
BackgroundThe neutrophil-to-lymphocyte ratio (NLR) and monocyte-to-lymphocyte ratio (MLR) are biomarkers that may reflect inflammatory status in some immune-related diseases. This study aims to investigate the association of NLR and MLR with the severity
Zhiwei Liu   +5 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Spotlight on the Disc-Damage Likelihood Scale (DDLS)

open access: yesClinical Ophthalmology, 2021
Kelvin KW Cheng, Andrew J Tatham Princess Alexandra Eye Pavilion, Edinburgh, UKCorrespondence: Andrew J TathamPrincess Alexandra Eye Pavilion, Edinburgh, UKTel +44 131 536 3753Email andrewjtatham@gmail.comAbstract: The disc damage likelihood scale (DDLS)
Cheng KKW, Tatham AJ
doaj  

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