Results 71 to 80 of about 7,589,280 (252)
Multi-scale hybrid numerical simulation of the growth of high-aspect-ratio nanostructures
, 2008 Recently, a variety high-aspect-ratio nanostructures have been grown and profiled for various applications ranging from field emission transistors to gene/drug delivery devices.
Ostrikov, K. +4 more
core +1 more source
PLoS Genetics, 2015 Despite the success of genome-wide association studies in medical genetics, the underlying genetics of many complex diseases remains enigmatic. One plausible reason for this could be the failure to account for the presence of genetic interactions in ...
Mattias Frånberg +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The diagnostic value of the ultrasound gray scale ratio for different sizes of thyroid nodules
Cancer Medicine, 2019 At present, hypoechogenicity, as one of the clinically relevant features associated with suspicion of malignant thyroid disease, is affected by the variability of modules and the experience of sonographers, thus leading to unsatisfying results.
Xiaoyu Chen +5 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Frontiers in Bioengineering and BiotechnologyRecent research has focused on issues related to contamination, nutrient availability, and strain selection, but there has been insufficient focus on harvesting research.
Hooi Ren Lim +3 more
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
, 2020 Unique view of the landscape and management of European scale-ups The widely held belief that European scale-ups are mainly innovative tech companies is incorrect; they can be found in all sectors and at all levels of innovation.
Collewaert, Veroniek +2 more
core
A moving model rig with a scale ratio of 1/8 for high speed train aerodynamics
, 2016 To achieve an accurate aerodynamic optimization of the outline of a high speed train and an experimental simulation of the meeting of two trains, especially in a tunnel, a train model in a moving model rig (MMR) should feature a large scale ratio and ...
Yang GW(杨国伟) +3 more
core +1 more source