Results 61 to 70 of about 7,589,280 (252)

An improved gray-scale transformation method for pseudo-color image enhancement [PDF]

Компьютерная оптика, 2019
Image enhancement is a very important process of image preprocessing and it plays a critical role in the improvement of image quality and the follow-up image analysis, which makes the research of image enhancement algorithm a hot research field.
Haibo Gao, Wenjuan Zeng, Jifeng Chen
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

CDSKNNXMBD: a novel clustering framework for large-scale single-cell data based on a stable graph structure

Journal of Translational Medicine
Background Accurate and efficient cell grouping is essential for analyzing single-cell transcriptome sequencing (scRNA-seq) data. However, the existing clustering techniques often struggle to provide timely and accurate cell type groupings when dealing ...
Jun Ren, Xuejing Lyu, Jintao Guo, Xiaodong Shi, Ying Zhou, Qiyuan Li   +5 more
doaj   +1 more source

Comparison of the classification ratios of four depression rating scales commonly used in Turkey

Psychiatry and Clinical Psychopharmacology, 2017
Objective: According to literature more than 20 depression scales are in use in Turkey. Considering that depression is a popular area of study, it may not seem abnormally unusual that there are so many measuring scales available.
Gaye Saltukoğlu, Arkun Tatar
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The male to female ratio at birth [PDF]

, 2014
The factors that influence the male to female ratio at birth are legion. Males are usually born in excess and stress decreases the ratio while wellbeing and good health tends to increase it.
Mamo, Julian, Grech, Victor E.
core   +1 more source

C-Reactive Protein, International Normalized Ratio, and Fibrinogen in Diagnostic Scale of Complicated Acute Appendicitis

Clinics and Practice
Background/Objectives: Differentiating complicated acute appendicitis (CA) and uncomplicated acute appendicitis (UC) is essential to guide clinical management.
Leticia Lorena Hernández-González, Said José Serrano-Guzmán, Jesús David Guzmán-Ortiz, Hermelo Esteban Pérez-Ceballos, José Luis Cano-Pérez, Víctor Cruz-Hernández, Héctor Ulises Bernardino-Hernández, Lucía Lourdes Martínez-Martínez, Sergio Roberto Aguilar-Ruiz   +8 more
doaj   +1 more source

Study The Role of Glasgow coma Scale, Neutrophil-Lymphocyte ratio, Platelet-Lymphocyte ratio, and Serum Creatinine as predictors of severity and mortality in acute organophosphorus poisoning [PDF]

Ain Shams Journal of Forensic Medicine and Clinical Toxicology
Background: Organophosphorus compounds (OPCs) are extremely toxic to humans. Aim: To evaluate the role of the Glasgow Coma Scale, Neutrophil-Lymphocyte ratio (NLR), Platelet-Lymphocyte ratio (PLR), and serum creatinine as predictors of severity and ...
Ghidaa Mohamed, Suszan Mostafa, Rabab Hafez, Salma Abdelkader   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source