Results 121 to 130 of about 15,576,713 (334)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

The Scale of Public Space: Taksim Square in Istanbul

Journal of Contemporary Urban Affairs, 2017
This article aims at following the traces of the transformation of public sphere in Turkey through its manifestations on urban public spaces with the case study of Taksim Square.
Senem Zeybekoglu Sadri
doaj   +1 more source

A time-causal and time-recursive scale-covariant scale-space representation of temporal signals and past time. [PDF]

Biol Cybern, 2023
Lindeberg T.
europepmc   +1 more source

Cosmological perturbations in inflationary models with anisotropic space-time scaling in a Lifshitz background [PDF]

, 2013
Mohsen Alishahiha, Hassan Firouzjahi, K. Koyama, Mohammad Hossein Namjoo   +3 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Safe operating space for humanity at a regional scale

Ecology and Society, 2018
The planetary boundaries framework defined safe limits to human impacts on essential Earth-system processes. Subsequent assessments concluded that impacts exceed most delineated boundaries.
John F. McLaughlin
doaj   +1 more source

Scale space detector for analyzing spatiotemporal ventricular contractility and nuclear morphogenesis in zebrafish. [PDF]

iScience, 2022
Teranikar T, Villarreal C, Salehin N, Ijaseun T, Lim J, Dominguez C, Nguyen V, Cao H, Chuong CJ, Lee J.   +9 more
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Isophotes, Scale Space, and Invariants in Lung CT for COPD Diagnosis. [PDF]

Radiol Artif Intell, 2022
Vannier MW.
europepmc   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source