Results 131 to 140 of about 9,624,872 (292)
Neural Representation of Multiple Spatial Scales
Shengwu huaxue yu shengwu wuli jinzhanSpatial environment includes multiple scales, which can be specifically divided into operable near-scale figural space, navigable space consisting of single-viewpoint space and environmental space, and large-scale geographic space.
WU Wen-Ya, WANG Liang
doaj +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Working the space: locating teachers’ voices in large-scale, mandated curriculum reform [PDF]
, 2016 The educational landscape is one of significant change. This thesis is concerned with the early responses of a group of teachers to large-scale, mandated curriculum reform at one independent P-12 school located in regional Queensland.
Evans, Donna Leigh
core
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Submersible Space Training Suit Preliminary Test Results and Review
Immediate accessThis item is made available by the University of Arizona Center for Human Space Exploration (CHaSE) with support from the University of Arizona Libraries.
Smith, Cameron, Tresch, Trent
core +4 more sources
Automatic Detection of Individual Trees from VHR Satellite Images Using Scale-Space Methods. [PDF]
Sensors (Basel), 2020 Mahour M, Tolpekin V, Stein A.
europepmc +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source