Results 131 to 140 of about 14,780,830 (367)
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Application of Fractal Image Analysis by Scale-Space Filtering in Experimental Mechanics. [PDF]
Bauer A, Volk W, Hartmann C.
europepmc +1 more source
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada+3 more
wiley +1 more source
nAdder: A scale-space approach for the 3D analysis of neuronal traces. [PDF]
Phan MS+4 more
europepmc +1 more source
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian+4 more
wiley +1 more source
Safe operating space for humanity at a regional scale
The planetary boundaries framework defined safe limits to human impacts on essential Earth-system processes. Subsequent assessments concluded that impacts exceed most delineated boundaries.
John F. McLaughlin
doaj +1 more source
A time-causal and time-recursive scale-covariant scale-space representation of temporal signals and past time. [PDF]
Lindeberg T.
europepmc +1 more source
Space and Time Scales of Atmospheric Variability [PDF]
Michael Stefanick
openalex +1 more source
Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee+9 more
wiley +1 more source