Results 91 to 100 of about 1,321,726 (316)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Validity of a brief workaholism scale. [PDF]
Psicothema, 2010 ESP
Líbano, M. +3 more
openaire +3 more sources
Experimental validation of unsteady models for fluid structure interaction: Application to yacht sails and rigs [PDF]
, 2012 • We present full scale measurements on a yacht sailing upwind in moderate head swell • We highlight the unsteadiness of the loads : peaks may be twice the mean value • The dynamic behavior differs from the steady state : hysteresis loop • Experimental ...
AUGIER, Benoit +3 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
“It Was Only Harmless Banter!” The development and preliminary validation of the moral disengagement in sexual harassment scale. [PDF]
, 2015 Sexual harassment represents aggressive behavior that is often enacted instrumentally, in response to a threatened sense of masculinity and male identity.
Page, Thomas E. +5 more
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Development and initial validation of the Music Mood-Regulation Scale (MMRS) [PDF]
, 2008 This study designed a measure to assess the perceived effectiveness of music as a strategy to regulate mood among a sport and exercise population. A strategy of assessing and comparing the integrity of competing hypotheses to explain the underlying ...
Lane, AM +8 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Development and initial validation of the Engagement in Athletic Training Scale [PDF]
The current study presents the development process and initial validation of the Engagement in Athletic Training Scale (EATS), which was designed to evaluate athletes’ engagement in athletic training.
Jun-Xia Wu +6 more
core +1 more source
The Organisational Life Cycle Scale: An Empirical Validation
, 2020 Organizational life cycle scales are widely relied upon by scholar and practitioners alike as a strategic tool to identify firms’ life cycle stages.
Al-Taie, Moyassar, Cater-Steel, Aileen
core +1 more source