Results 111 to 120 of about 7,437,410 (311)

The validity of the Telic Dominance Scale [PDF]

, 1984
The Telic Dominance Scale (TDS) is a 42 item pencil and paper psychometric instrument intended to measure the extent to which a person is seriousminded, planning orientated, arousal avoiding and telic or paratelic dominant. Using test related reliability methods, this study demonstrates that the TDS is a reliable instrument over a variety of time ...
openaire   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Development and Validation of a Comprehensive Oral Health Knowledge and Behavior Scale

Journal of Pharmacy and Bioallied Sciences
Background: Oral health knowledge and behaviors are crucial for preventing oral diseases; however, existing tools lack comprehensiveness and standardization.
Kunal Jha, Ipseeta Menon, Rutuja P. Sindgi, Shilpa Duseja, Lavanya H. Pasalkar, Sreyas Vellanki   +5 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Validating a measure of motivational regulation strategies and examining their relationship to English proficiency

Studies in Second Language Learning and Teaching
Motivational regulation has been recognized as a crucial component of self-regulated learning. This paper presents the validation of a measure of motivational regulation strategies in an English as a foreign language context (MRS-EFL).
Sha Luo, Zhengdong Gan, Zhujun An
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Reliability and validity of the authentic leadership questionnaire: evidence from Vietnamese higher education

Frontiers in Education
IntroductionAuthentic leadership has emerged as a crucial concept in organizational and educational research; however, its assessment has not been adequately explored in non-Western contexts, particularly within Vietnamese higher education.
Van Dat Tran, Minh Tuan Lam Le, Thi Kim Ngan Nguyen, Thi Cam Huynh   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Estudio psicométrico del cuestionario de intenciones emprendedoras en jóvenes mexicanos - Psychometric study of the entrepreneurial intentions questionnaire in Mexican youth

Suma de Negocios
Introducción/objetivo: el emprendimiento se ha consolidado como un motor clave para el crecimiento personal y el desarrollo económico en distintos ámbitos.
Ignacio Norambuena , Felipe Quintano , Leonor Riquelme , José Sepúlveda, Cristina Tavera , Selene Pérez , Crisóforo Álvarez, Roque López   +7 more
doaj   +1 more source

The Behavioural Dyscontrol Scale-Validation of a computerised version in a non-clinical New Zealand population [PDF]

, 2013
The objective of this study was to evaluate the validity of a new computerised version of the Behavioural Dyscontrol Scale (BDS) in comparison to the original manual version which research has shown to be a sensitive, reliable and valid measure of ...
Kendall, Virginia Ruth
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