Results 101 to 110 of about 7,437,410 (311)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Validation of the French version of the Body Awareness Questionnaire: toward a way to assess alexisomia

Frontiers in Psychology
BackgroundAwareness of one's own states is a particularly important part of cognition and emotion regulation. Recently, the concept of alexisomia has been used to refer to lack of awareness and expression of somatic sensations.
Arnaud Carre, Rebecca Shankland, Philippe Guillaume, Jeanne Duclos, Claire El-Jor, Sonia Pellissier, Valentin Flaudias, Valentin Flaudias   +7 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Sensitivity to Pain Traumatization Scale: development, validation, and preliminary findings

, 2017
Joel Katz,1,2 Samantha R Fashler,1 Claire Wicks,1 M Gabrielle Pagé,3 Kaley M Roosen,1 Valery Kleiman,1 Hance Clarke2 1Department of Psychology, York University, 2Department of Anesthesia and Pain Management, Toronto General Hospital, Toronto, ON ...
Kleiman V, Clarke H, Fashler SR, Roosen KM, Pagé MG, Wicks C, Katz J   +6 more
core  

The Organisational Life Cycle Scale: An Empirical Validation

, 2020
Organizational life cycle scales are widely relied upon by scholar and practitioners alike as a strategic tool to identify firms’ life cycle stages.
Al-Taie, Moyassar, Cater-Steel, Aileen
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Psychometric Properties of the Serbian Teen Version of the Problem Areas in Diabetes Scale—A Validation Study

Nursing Reports
Screening for diabetes-specific distress should be considered a standard component of diabetes management. This study aimed to evaluate the psychometric properties of the Serbian adaptation of the Problem Areas in Diabetes—Teen Version (PAID-T). Methods:
Mirjana Smudja, Tatjana Milenković, Ivana Minaković, Vera Zdravković, Sandra Mitić, Ana Miljković, Dragana Milutinović   +6 more
doaj   +1 more source

Creation and validation of the belief in the supernatural scale

, 2018
This study aimed to create and validate a new scale, the “Belief in the Supernatural Scale.” Study one used an Exploratory Factor Analysis (EFA) to reduce an initial item pool of 71 items to 44 and to identify a factor structure with 382 participants.
Schofield, M.B., Baker, I.S., Sheffield, D., Staples, P.   +3 more
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Adaptation of e-health impact questionnaire into Turkish: a validity and reliability study

Frontiers in Digital Health
Introductione-Health refers to the use of information and communication technologies (ICT) for health-related services. e-Health aims to distribute scarce resources to areas in need more efficiently and to reduce the cost of health care delivery. However,
Mustafa Kafes, Serife Didem Kaya
doaj   +1 more source